Construction, characterization, and evaluation of nanosized curdlan sulfate/quaternary ammonium chitosan/CpG ODN polyelectrolyte complex as an adjuvant for tumor vaccine.

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Title: Construction, characterization, and evaluation of nanosized curdlan sulfate/quaternary ammonium chitosan/CpG ODN polyelectrolyte complex as an adjuvant for tumor vaccine.
Authors: Li Z; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China; Shandong College of Traditional Chinese Medicine, Yantai, 264199, Shandong, China., Zhang Y; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China., Chen Y; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China., Liu M; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China., Li P; Phase 1 Clinical Trial Center, Qilu Hospital of Shandong University, Jinan, 250012, Shandong, China., Wang F; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China; NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate-based Medicine, National Glycoengineering Research Center, Shandong University, Jinan, 250012, Shandong, China; Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Jinan, 250012, Shandong, China. Electronic address: fswang@sdu.edu.cn., Jiang W; State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China; NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate-based Medicine, National Glycoengineering Research Center, Shandong University, Jinan, 250012, Shandong, China. Electronic address: w.jiang@sdu.edu.cn.
Source: International journal of biological macromolecules [Int J Biol Macromol] 2026 Jun; Vol. 366, pp. 152491. Date of Electronic Publication: 2026 May 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0003
DOI:10.1016/j.ijbiomac.2026.152491