An RHD gene variant, common in southern Chinese Han, involves a short 688 bp deletion and a long 21.8 kb insertion in the RHD exon 10 non-coding region, affecting the accuracy of red cell genotyping.

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Title: An RHD gene variant, common in southern Chinese Han, involves a short 688 bp deletion and a long 21.8 kb insertion in the RHD exon 10 non-coding region, affecting the accuracy of red cell genotyping.
Authors: Wen J; Institute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China.; The Key Medical Laboratory of Guangzhou, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China., He F; Department of Blood Transfusion, The First Affiliated Hospital of Guangxi Medical University, Nanning, China., Veldhuisen B; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Mo C; Institute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China.; The Key Medical Laboratory of Guangzhou, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China., Wei L; Institute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China.; The Key Medical Laboratory of Guangzhou, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China., Jia S; Institute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China.; The Key Medical Laboratory of Guangzhou, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China., van der Schoot CE; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Flegel WA; Department of Transfusion Medicine, NIH Clinical Center, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892-1184, USA. waf@nih.gov., Ji Y; Institute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China. jiyanli2013@163.com.; The Key Medical Laboratory of Guangzhou, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China. jiyanli2013@163.com.
Source: Journal of translational medicine [J Transl Med] 2026 May 12; Vol. 24 (1). Date of Electronic Publication: 2026 May 12.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An RHD gene variant, common in southern Chinese Han, involves a short 688 bp deletion and a long 21.8 kb insertion in the RHD exon 10 non-coding region, affecting the accuracy of red cell genotyping.
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  Data: <searchLink fieldCode="AU" term="%22Wen+J%22">Wen J</searchLink>; Institute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China.; The Key Medical Laboratory of Guangzhou, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China.<br /><searchLink fieldCode="AU" term="%22He+F%22">He F</searchLink>; Department of Blood Transfusion, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Veldhuisen+B%22">Veldhuisen B</searchLink>; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mo+C%22">Mo C</searchLink>; Institute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China.; The Key Medical Laboratory of Guangzhou, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China.<br /><searchLink fieldCode="AU" term="%22Wei+L%22">Wei L</searchLink>; Institute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China.; The Key Medical Laboratory of Guangzhou, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China.<br /><searchLink fieldCode="AU" term="%22Jia+S%22">Jia S</searchLink>; Institute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China.; The Key Medical Laboratory of Guangzhou, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China.<br /><searchLink fieldCode="AU" term="%22van+der+Schoot+CE%22">van der Schoot CE</searchLink>; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Flegel+WA%22">Flegel WA</searchLink>; Department of Transfusion Medicine, NIH Clinical Center, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892-1184, USA. waf@nih.gov.<br /><searchLink fieldCode="AU" term="%22Ji+Y%22">Ji Y</searchLink>; Institute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China. jiyanli2013@163.com.; The Key Medical Laboratory of Guangzhou, No31, Luyuan Road, Yuexiu District, Guangzhou, 510095, China. jiyanli2013@163.com.
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  Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2026 May 12; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 May 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190741 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-5876 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214795876%22">14795876 </searchLink><i>NLM ISO Abbreviation: </i>J Transl Med <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12967-026-08183-1
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        Text: English
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      – TitleFull: An RHD gene variant, common in southern Chinese Han, involves a short 688 bp deletion and a long 21.8 kb insertion in the RHD exon 10 non-coding region, affecting the accuracy of red cell genotyping.
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              Text: 2026 May 12
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