Multiscale molecular modeling-directed ROS-responsive nanotherapy for dual-axis regulation of fibrotic and inflammatory signaling in alport nephropathy.

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Title: Multiscale molecular modeling-directed ROS-responsive nanotherapy for dual-axis regulation of fibrotic and inflammatory signaling in alport nephropathy.
Authors: Choi HS; Department of Internal Medicine, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea., Sundaram A; Department of Biomedical Sciences, Biomedical Sciences Graduate Program (BMSGP), Chonnam National University Medical School, Chonnam National University, 322 Seoyang-ro, Hwasun-gun, Hwasun, 58128, Jeollanam-do, Republic of Korea.; DR Cure Inc., Hwasun, 58128, Republic of Korea., Vasukutty A; Department of Biomedical Sciences, Biomedical Sciences Graduate Program (BMSGP), Chonnam National University Medical School, Chonnam National University, 322 Seoyang-ro, Hwasun-gun, Hwasun, 58128, Jeollanam-do, Republic of Korea., Mathew AP; Department of Chemical and Biological Engineering, Iowa State University, Iowa, USA.; Nanovaccine Institute, Iowa State University, Iowa, USA., Sathiyamoorthy P; Department of Biomedical Sciences, Biomedical Sciences Graduate Program (BMSGP), Chonnam National University Medical School, Chonnam National University, 322 Seoyang-ro, Hwasun-gun, Hwasun, 58128, Jeollanam-do, Republic of Korea., Kim IJ; Department of Internal Medicine, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea., Suh SH; Department of Internal Medicine, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea., Kim CS; Department of Internal Medicine, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea., Ma SK; Department of Internal Medicine, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea., Kim SW; Department of Internal Medicine, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea., Park IK; Department of Biomedical Sciences, Biomedical Sciences Graduate Program (BMSGP), Chonnam National University Medical School, Chonnam National University, 322 Seoyang-ro, Hwasun-gun, Hwasun, 58128, Jeollanam-do, Republic of Korea. pik96@jnu.ac.kr.; DR Cure Inc., Hwasun, 58128, Republic of Korea. pik96@jnu.ac.kr., Bae EH; Department of Internal Medicine, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea. baedak76@gmail.com.; Department of Internal Medicine, Chonnam National University Medical School, 42 Jebong-ro, Dong-gu, Gwangju, 61469, Republic of Korea. baedak76@gmail.com.
Source: Journal of nanobiotechnology [J Nanobiotechnology] 2026 May 12; Vol. 24 (1). Date of Electronic Publication: 2026 May 12.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1477-3155
DOI:10.1186/s12951-026-04451-w