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Isomer-Dependent Pharmacokinetic Behavior and VKOR Interactions of Second-Generation Anticoagulant Rodenticides: An Integrated In Vivo-In Vitro-In Silico Investigation.

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Title: Isomer-Dependent Pharmacokinetic Behavior and VKOR Interactions of Second-Generation Anticoagulant Rodenticides: An Integrated In Vivo-In Vitro-In Silico Investigation.
Authors: Miyamae M; Laboratory of Toxicology, School of Veterinary Medicine, Kitasato University, Towada 034-0021, Japan., Nagaoka S; Daimaru Compound Chemical Co., Ltd., Nagano 381-1222, Japan., Hayama T; Laboratory of Toxicology, School of Veterinary Medicine, Kitasato University, Towada 034-0021, Japan., Fukamatsu M; Laboratory of Toxicology, School of Veterinary Medicine, Kitasato University, Towada 034-0021, Japan., Kamata R; Laboratory of Toxicology, School of Veterinary Medicine, Kitasato University, Towada 034-0021, Japan., Takeda K; Laboratory of Toxicology, School of Veterinary Medicine, Kitasato University, Towada 034-0021, Japan.; School of Computing, Institute of Science Tokyo, Tokyo 152-8552, Japan.
Source: International journal of molecular sciences [Int J Mol Sci] 2026 Apr 24; Vol. 27 (9). Date of Electronic Publication: 2026 Apr 24.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Isomer-Dependent Pharmacokinetic Behavior and VKOR Interactions of Second-Generation Anticoagulant Rodenticides: An Integrated In Vivo-In Vitro-In Silico Investigation.
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  Data: <searchLink fieldCode="AU" term="%22Miyamae+M%22">Miyamae M</searchLink>; Laboratory of Toxicology, School of Veterinary Medicine, Kitasato University, Towada 034-0021, Japan.<br /><searchLink fieldCode="AU" term="%22Nagaoka+S%22">Nagaoka S</searchLink>; Daimaru Compound Chemical Co., Ltd., Nagano 381-1222, Japan.<br /><searchLink fieldCode="AU" term="%22Hayama+T%22">Hayama T</searchLink>; Laboratory of Toxicology, School of Veterinary Medicine, Kitasato University, Towada 034-0021, Japan.<br /><searchLink fieldCode="AU" term="%22Fukamatsu+M%22">Fukamatsu M</searchLink>; Laboratory of Toxicology, School of Veterinary Medicine, Kitasato University, Towada 034-0021, Japan.<br /><searchLink fieldCode="AU" term="%22Kamata+R%22">Kamata R</searchLink>; Laboratory of Toxicology, School of Veterinary Medicine, Kitasato University, Towada 034-0021, Japan.<br /><searchLink fieldCode="AU" term="%22Takeda+K%22">Takeda K</searchLink>; Laboratory of Toxicology, School of Veterinary Medicine, Kitasato University, Towada 034-0021, Japan.; School of Computing, Institute of Science Tokyo, Tokyo 152-8552, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101092791%22">International journal of molecular sciences</searchLink> [Int J Mol Sci] 2026 Apr 24; Vol. 27 (9). <i>Date of Electronic Publication: </i>2026 Apr 24.
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