Semaglutide, at a dose that produces modest weight loss, induces mild suppression of bone remodeling in healthy control rats and those with chronic kidney disease.

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Title: Semaglutide, at a dose that produces modest weight loss, induces mild suppression of bone remodeling in healthy control rats and those with chronic kidney disease.
Authors: Allen MR; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, United States of America; Department of Medicine, Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, United States of America; Roudebush VA, Indianapolis, IN, United States of America. Electronic address: matallen@iu.edu., Metzger CE; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, United States of America., Chen NX; Department of Medicine, Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, United States of America., Tinsley IC; Department of Chemistry, Indiana University, Bloomington, IN, United States of America., DiMarchi RD; Department of Chemistry, Indiana University, Bloomington, IN, United States of America., O'Neill K; Department of Medicine, Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, United States of America., Matter EK; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, United States of America., Moe SM; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, United States of America; Department of Medicine, Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, United States of America.
Source: Bone [Bone] 2026 Sep; Vol. 210, pp. 117933. Date of Electronic Publication: 2026 May 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8504048 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2763 (Electronic) Linking ISSN: 18732763 NLM ISO Abbreviation: Bone Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Allen+MR%22">Allen MR</searchLink>; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, United States of America; Department of Medicine, Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, United States of America; Roudebush VA, Indianapolis, IN, United States of America. Electronic address: matallen@iu.edu.<br /><searchLink fieldCode="AU" term="%22Metzger+CE%22">Metzger CE</searchLink>; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, United States of America.<br /><searchLink fieldCode="AU" term="%22Chen+NX%22">Chen NX</searchLink>; Department of Medicine, Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, United States of America.<br /><searchLink fieldCode="AU" term="%22Tinsley+IC%22">Tinsley IC</searchLink>; Department of Chemistry, Indiana University, Bloomington, IN, United States of America.<br /><searchLink fieldCode="AU" term="%22DiMarchi+RD%22">DiMarchi RD</searchLink>; Department of Chemistry, Indiana University, Bloomington, IN, United States of America.<br /><searchLink fieldCode="AU" term="%22O'Neill+K%22">O'Neill K</searchLink>; Department of Medicine, Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, United States of America.<br /><searchLink fieldCode="AU" term="%22Matter+EK%22">Matter EK</searchLink>; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, United States of America.<br /><searchLink fieldCode="AU" term="%22Moe+SM%22">Moe SM</searchLink>; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, United States of America; Department of Medicine, Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, United States of America.
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  Data: <searchLink fieldCode="JN" term="%228504048%22">Bone</searchLink> [Bone] 2026 Sep; Vol. 210, pp. 117933. <i>Date of Electronic Publication: </i>2026 May 12.
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        Value: 10.1016/j.bone.2026.117933
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      – TitleFull: Semaglutide, at a dose that produces modest weight loss, induces mild suppression of bone remodeling in healthy control rats and those with chronic kidney disease.
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              Text: 2026 Sep
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