Schizantherin B alleviates cisplatin-induced ototoxicity and does not interfere cisplatin-based chemotherapy in a breast cancer model.

Saved in:
Bibliographic Details
Title: Schizantherin B alleviates cisplatin-induced ototoxicity and does not interfere cisplatin-based chemotherapy in a breast cancer model.
Authors: Zhao Z; ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.; Institute of Biomedical Science, Fudan University, Shanghai, 200031, China.; NHC Key Laboratory of Hearing Medicine, Fudan University, Shanghai, 200031, China.; Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200031, China.; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200031, China.; Department of Otolaryngology, Yueyang Hospital of Integrative Chinese & Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China., Han L; ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.; Institute of Biomedical Science, Fudan University, Shanghai, 200031, China.; NHC Key Laboratory of Hearing Medicine, Fudan University, Shanghai, 200031, China.; Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200031, China.; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200031, China.; Department of Otorhinolaryngology, The Second Affiliated Hospital, University of South China, Hengyang, 421001, China., Xu Z; ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.; Institute of Biomedical Science, Fudan University, Shanghai, 200031, China.; NHC Key Laboratory of Hearing Medicine, Fudan University, Shanghai, 200031, China.; Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200031, China.; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200031, China.; Anhui Province Key Laboratory of Biomedical Imaging and Intelligent Processing, Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, 230088, China., Nan B; Department of Otorhinolaryngology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, China., Tang H; ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.; Institute of Biomedical Science, Fudan University, Shanghai, 200031, China.; NHC Key Laboratory of Hearing Medicine, Fudan University, Shanghai, 200031, China.; Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200031, China.; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200031, China., Dong D; ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.; Institute of Biomedical Science, Fudan University, Shanghai, 200031, China.; NHC Key Laboratory of Hearing Medicine, Fudan University, Shanghai, 200031, China.; Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200031, China.; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200031, China., Zen Z; Department of ENT of the Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221000, China., Gao Z; ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.; Institute of Biomedical Science, Fudan University, Shanghai, 200031, China.; NHC Key Laboratory of Hearing Medicine, Fudan University, Shanghai, 200031, China.; Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200031, China.; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200031, China., Ye C; ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.; Institute of Biomedical Science, Fudan University, Shanghai, 200031, China.; NHC Key Laboratory of Hearing Medicine, Fudan University, Shanghai, 200031, China.; Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200031, China.; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200031, China., Huang X; Department of Otorhinolaryngology-Head and Neck Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200030, China. huang.xinsheng@zs-hospital.sh.cn., Zhang J; Department of Otolaryngology, Yueyang Hospital of Integrative Chinese & Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China. eternityz@sina.com., Li GL; ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China. genglin.li@fdeent.org.; Institute of Biomedical Science, Fudan University, Shanghai, 200031, China. genglin.li@fdeent.org.; NHC Key Laboratory of Hearing Medicine, Fudan University, Shanghai, 200031, China. genglin.li@fdeent.org., Shu Y; ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China. yilai_shu@fudan.edu.cn.; Institute of Biomedical Science, Fudan University, Shanghai, 200031, China. yilai_shu@fudan.edu.cn.; NHC Key Laboratory of Hearing Medicine, Fudan University, Shanghai, 200031, China. yilai_shu@fudan.edu.cn.; Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200031, China. yilai_shu@fudan.edu.cn.; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200031, China. yilai_shu@fudan.edu.cn.
Source: Archives of toxicology [Arch Toxicol] 2026 May 13. Date of Electronic Publication: 2026 May 13.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1432-0738
DOI:10.1007/s00204-026-04410-2