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Spatial lipidomic and neuron-specific transcriptomic signatures in the nucleus accumbens reveal phospholipid dyshomeostasis in depression-related maladaptations.

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Title: Spatial lipidomic and neuron-specific transcriptomic signatures in the nucleus accumbens reveal phospholipid dyshomeostasis in depression-related maladaptations.
Authors: Camargo A; Department of Clinical Neuroscience, Translational Research on Neuropharmacology and Movement Disorders, Karolinska Institutet, Stockholm, Sweden. anderson.camargo@ki.se., Kaya I; Department of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Sturchio A; Department of Clinical Neuroscience, Translational Research on Neuropharmacology and Movement Disorders, Karolinska Institutet, Stockholm, Sweden., Saarinen M; Department of Clinical Neuroscience, Translational Research on Neuropharmacology and Movement Disorders, Karolinska Institutet, Stockholm, Sweden., Kurgina A; Department of Clinical Neuroscience, Translational Research on Neuropharmacology and Movement Disorders, Karolinska Institutet, Stockholm, Sweden., Liang T; Department of Clinical Neuroscience, Translational Research on Neuropharmacology and Movement Disorders, Karolinska Institutet, Stockholm, Sweden., Andrén PE; Department of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Svenningsson P; Department of Clinical Neuroscience, Translational Research on Neuropharmacology and Movement Disorders, Karolinska Institutet, Stockholm, Sweden. per.svenningsson@ki.se.
Source: Translational psychiatry [Transl Psychiatry] 2026 May 14; Vol. 16 (1). Date of Electronic Publication: 2026 May 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Camargo+A%22">Camargo A</searchLink>; Department of Clinical Neuroscience, Translational Research on Neuropharmacology and Movement Disorders, Karolinska Institutet, Stockholm, Sweden. anderson.camargo@ki.se.<br /><searchLink fieldCode="AU" term="%22Kaya+I%22">Kaya I</searchLink>; Department of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Sturchio+A%22">Sturchio A</searchLink>; Department of Clinical Neuroscience, Translational Research on Neuropharmacology and Movement Disorders, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Saarinen+M%22">Saarinen M</searchLink>; Department of Clinical Neuroscience, Translational Research on Neuropharmacology and Movement Disorders, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Kurgina+A%22">Kurgina A</searchLink>; Department of Clinical Neuroscience, Translational Research on Neuropharmacology and Movement Disorders, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Liang+T%22">Liang T</searchLink>; Department of Clinical Neuroscience, Translational Research on Neuropharmacology and Movement Disorders, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Andrén+PE%22">Andrén PE</searchLink>; Department of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Svenningsson+P%22">Svenningsson P</searchLink>; Department of Clinical Neuroscience, Translational Research on Neuropharmacology and Movement Disorders, Karolinska Institutet, Stockholm, Sweden. per.svenningsson@ki.se.
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              Text: 2026 May 14
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