Impaired glymphatic function and advanced brain age gap in chronic migraine: a multimodal MRI study.

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Title: Impaired glymphatic function and advanced brain age gap in chronic migraine: a multimodal MRI study.
Authors: Dai C; Department of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Neurogenetics, Wenzhou, Zhejiang, 325027, China., Fu F; Department of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Neurogenetics, Wenzhou, Zhejiang, 325027, China., Guo Y; Department of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Neurogenetics, Wenzhou, Zhejiang, 325027, China., Liu X; Department of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Neurogenetics, Wenzhou, Zhejiang, 325027, China., Tao Z; Department of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Neurogenetics, Wenzhou, Zhejiang, 325027, China., Zhang X; Department of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Neurogenetics, Wenzhou, Zhejiang, 325027, China., Li X; Department of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Neurogenetics, Wenzhou, Zhejiang, 325027, China., Lin C; Department of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Neurogenetics, Wenzhou, Zhejiang, 325027, China., Ye M; Department of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Neurogenetics, Wenzhou, Zhejiang, 325027, China., Huang M; Department of Radiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Structural and Functional Imaging, Wenzhou, Zhejiang, 325027, China., Hu Y; Department of Radiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Structural and Functional Imaging, Wenzhou, Zhejiang, 325027, China., Liu K; Department of Radiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Structural and Functional Imaging, Wenzhou, Zhejiang, 325027, China., Cao Y; Department of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Neurogenetics, Wenzhou, Zhejiang, 325027, China., Chen K; Department of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Neurogenetics, Wenzhou, Zhejiang, 325027, China., Hu B; Department of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.; Wenzhou Key Laboratory of Neurogenetics, Wenzhou, Zhejiang, 325027, China., Liu X; Department of Radiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China. lxz_2088@hotmail.com.; Wenzhou Key Laboratory of Structural and Functional Imaging, Wenzhou, Zhejiang, 325027, China. lxz_2088@hotmail.com., Li Y; Department of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China. yanli@wzhealth.com.; Wenzhou Key Laboratory of Neurogenetics, Wenzhou, Zhejiang, 325027, China. yanli@wzhealth.com.
Source: The journal of headache and pain [J Headache Pain] 2026 May 13; Vol. 27 (1). Date of Electronic Publication: 2026 May 13.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1129-2377
DOI:10.1186/s10194-026-02384-1