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Regular human insulins versus rapid-acting insulin analogues in children and adolescents with type 1 diabetes: a systematic review with meta-analysis and trial sequential analysis.

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Title: Regular human insulins versus rapid-acting insulin analogues in children and adolescents with type 1 diabetes: a systematic review with meta-analysis and trial sequential analysis.
Authors: Petersen JJ; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen, Denmark johanne.juul.petersen@ctu.dk.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Faltermeier P; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen, Denmark., Juul S; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen, Denmark.; Mental Health Services in the Capital Region of Denmark, Psykoterapeutisk Center Stolpegard, Gentofte, Denmark.; Department of Psychology, University of Copenhagen, Copenhagen, Denmark., Kamp CB; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen, Denmark., Sillassen CDB; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen, Denmark.; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.; Department of Cardiology, Central and West Zealand Hospital, Slagelse, Denmark., Dos Santos TJ; Unit of Pediatrics, Hospital Vithas Almería, Instituto Hispalense de Pediatría SL, Seville, Spain.; Department of Nursing Physiotherapy and Medicine, Faculty of Health Sciences, University of Almeria, Almería, Spain., Jakobsen JC; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen, Denmark.; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Source: BMJ open [BMJ Open] 2026 May 14; Vol. 16 (5), pp. e100186. Date of Electronic Publication: 2026 May 14.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Regular human insulins versus rapid-acting insulin analogues in children and adolescents with type 1 diabetes: a systematic review with meta-analysis and trial sequential analysis.
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  Data: <searchLink fieldCode="AU" term="%22Petersen+JJ%22">Petersen JJ</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen, Denmark johanne.juul.petersen@ctu.dk.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Faltermeier+P%22">Faltermeier P</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Juul+S%22">Juul S</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen, Denmark.; Mental Health Services in the Capital Region of Denmark, Psykoterapeutisk Center Stolpegard, Gentofte, Denmark.; Department of Psychology, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Kamp+CB%22">Kamp CB</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Sillassen+CDB%22">Sillassen CDB</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen, Denmark.; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.; Department of Cardiology, Central and West Zealand Hospital, Slagelse, Denmark.<br /><searchLink fieldCode="AU" term="%22Dos+Santos+TJ%22">Dos Santos TJ</searchLink>; Unit of Pediatrics, Hospital Vithas Almería, Instituto Hispalense de Pediatría SL, Seville, Spain.; Department of Nursing Physiotherapy and Medicine, Faculty of Health Sciences, University of Almeria, Almería, Spain.<br /><searchLink fieldCode="AU" term="%22Jakobsen+JC%22">Jakobsen JC</searchLink>; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen, Denmark.; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BMJ+Publishing+Group+Ltd%22">BMJ Publishing Group Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101552874 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2044-6055 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220446055%22">20446055 </searchLink><i>NLM ISO Abbreviation: </i>BMJ Open <i>Subsets: </i>MEDLINE
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