Heterozygous loss-of-function alleles associate the conserved 3'-5' exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5-fluorouracil.
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| Title: | Heterozygous loss-of-function alleles associate the conserved 3'-5' exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5-fluorouracil. |
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| Authors: | Sain R; Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Univ Rennes, Rennes, France., Le Page Y; Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Univ Rennes, Rennes, France., Percevault F; Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Univ Rennes, Rennes, France., Becker E; Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Univ Rennes, Rennes, France., Negroni L; ESBS, -BCS-UMR7242, Illkirch, France., Fernandez A; National Centre of Biotechnology (CNB-CSIC), Madrid, Spain.; Biomedical Research Networking Center on Rare Diseases (CIBERER-ISCIII), Madrid, Spain., Cantero M; National Centre of Biotechnology (CNB-CSIC), Madrid, Spain.; Biomedical Research Networking Center on Rare Diseases (CIBERER-ISCIII), Madrid, Spain., Muñoz-Santos D; National Centre of Biotechnology (CNB-CSIC), Madrid, Spain.; Biomedical Research Networking Center on Rare Diseases (CIBERER-ISCIII), Madrid, Spain.; Department of Medicine. Faculty of Medicine, Health and Sports, Universidad Europea de Madrid, Madrid, Spain., Montoliu L; National Centre of Biotechnology (CNB-CSIC), Madrid, Spain.; Biomedical Research Networking Center on Rare Diseases (CIBERER-ISCIII), Madrid, Spain., Garnier C; Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Univ Rennes, Rennes, France., Primig M; Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Univ Rennes, Rennes, France. |
| Source: | Molecular oncology [Mol Oncol] 2026 May 15. Date of Electronic Publication: 2026 May 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42138069 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Heterozygous loss-of-function alleles associate the conserved 3'-5' exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5-fluorouracil. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Sain+R%22">Sain R</searchLink>; Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR&#95;S 1085, Univ Rennes, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Le+Page+Y%22">Le Page Y</searchLink>; Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR&#95;S 1085, Univ Rennes, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Percevault+F%22">Percevault F</searchLink>; Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR&#95;S 1085, Univ Rennes, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Becker+E%22">Becker E</searchLink>; Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR&#95;S 1085, Univ Rennes, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Negroni+L%22">Negroni L</searchLink>; ESBS, -BCS-UMR7242, Illkirch, France.<br /><searchLink fieldCode="AU" term="%22Fernandez+A%22">Fernandez A</searchLink>; National Centre of Biotechnology (CNB-CSIC), Madrid, Spain.; Biomedical Research Networking Center on Rare Diseases (CIBERER-ISCIII), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Cantero+M%22">Cantero M</searchLink>; National Centre of Biotechnology (CNB-CSIC), Madrid, Spain.; Biomedical Research Networking Center on Rare Diseases (CIBERER-ISCIII), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Muñoz-Santos+D%22">Muñoz-Santos D</searchLink>; National Centre of Biotechnology (CNB-CSIC), Madrid, Spain.; Biomedical Research Networking Center on Rare Diseases (CIBERER-ISCIII), Madrid, Spain.; Department of Medicine. Faculty of Medicine, Health and Sports, Universidad Europea de Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Montoliu+L%22">Montoliu L</searchLink>; National Centre of Biotechnology (CNB-CSIC), Madrid, Spain.; Biomedical Research Networking Center on Rare Diseases (CIBERER-ISCIII), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Garnier+C%22">Garnier C</searchLink>; Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR&#95;S 1085, Univ Rennes, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Primig+M%22">Primig M</searchLink>; Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR&#95;S 1085, Univ Rennes, Rennes, France. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101308230%22">Molecular oncology</searchLink> [Mol Oncol] 2026 May 15. <i>Date of Electronic Publication: </i>2026 May 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Inc%22">John Wiley & Sons, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101308230 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-0261 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215747891%22">15747891 </searchLink><i>NLM ISO Abbreviation: </i>Mol Oncol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42138069 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/1878-0261.70239 Languages: – Code: eng Text: English Titles: – TitleFull: Heterozygous loss-of-function alleles associate the conserved 3'-5' exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5-fluorouracil. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sain R – PersonEntity: Name: NameFull: Le Page Y – PersonEntity: Name: NameFull: Percevault F – PersonEntity: Name: NameFull: Becker E – PersonEntity: Name: NameFull: Negroni L – PersonEntity: Name: NameFull: Fernandez A – PersonEntity: Name: NameFull: Cantero M – PersonEntity: Name: NameFull: Muñoz-Santos D – PersonEntity: Name: NameFull: Montoliu L – PersonEntity: Name: NameFull: Garnier C – PersonEntity: Name: NameFull: Primig M IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 05 Text: 2026 May 15 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1878-0261 Titles: – TitleFull: Molecular oncology Type: main |
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