The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells.

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Title: The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells.
Authors: Lefrançois G; Department of Chemistry, University of Montreal, Montreal, Canada.; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada., Lavallée E; Faculté de Pharmacie, University of Montreal, Montreal, Canada., Rowell MC; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada., Bourdeau V; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada., Mohebali F; Department of Chemistry, University of Montreal, Montreal, Canada., Bertomeu T; Institute for Research in Immunology and Cancer, University of Montreal, Montreal, Canada., Duman AM; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada., Nikolova M; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada., Tyers M; Institute for Research in Immunology and Cancer, University of Montreal, Montreal, Canada., Gravel SP; Faculté de Pharmacie, University of Montreal, Montreal, Canada.; Institute for Research in Immunology and Cancer, University of Montreal, Montreal, Canada., Schmitzer AR; Department of Chemistry, University of Montreal, Montreal, Canada., Ferbeyre G; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada.
Source: ELife [Elife] 2026 May 15; Vol. 13. Date of Electronic Publication: 2026 May 15.
Publication Type: Journal Article
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2050-084X
DOI:10.7554/eLife.102680