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The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells.

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Title: The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells.
Authors: Lefrançois G; Department of Chemistry, University of Montreal, Montreal, Canada.; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada., Lavallée E; Faculté de Pharmacie, University of Montreal, Montreal, Canada., Rowell MC; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada., Bourdeau V; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada., Mohebali F; Department of Chemistry, University of Montreal, Montreal, Canada., Bertomeu T; Institute for Research in Immunology and Cancer, University of Montreal, Montreal, Canada., Duman AM; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada., Nikolova M; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada., Tyers M; Institute for Research in Immunology and Cancer, University of Montreal, Montreal, Canada., Gravel SP; Faculté de Pharmacie, University of Montreal, Montreal, Canada.; Institute for Research in Immunology and Cancer, University of Montreal, Montreal, Canada., Schmitzer AR; Department of Chemistry, University of Montreal, Montreal, Canada., Ferbeyre G; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada.
Source: ELife [Elife] 2026 May 15; Vol. 13. Date of Electronic Publication: 2026 May 15.
Publication Type: Journal Article
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Lefrançois+G%22">Lefrançois G</searchLink>; Department of Chemistry, University of Montreal, Montreal, Canada.; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Lavallée+E%22">Lavallée E</searchLink>; Faculté de Pharmacie, University of Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Rowell+MC%22">Rowell MC</searchLink>; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Bourdeau+V%22">Bourdeau V</searchLink>; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Mohebali+F%22">Mohebali F</searchLink>; Department of Chemistry, University of Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Bertomeu+T%22">Bertomeu T</searchLink>; Institute for Research in Immunology and Cancer, University of Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Duman+AM%22">Duman AM</searchLink>; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Nikolova+M%22">Nikolova M</searchLink>; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Tyers+M%22">Tyers M</searchLink>; Institute for Research in Immunology and Cancer, University of Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Gravel+SP%22">Gravel SP</searchLink>; Faculté de Pharmacie, University of Montreal, Montreal, Canada.; Institute for Research in Immunology and Cancer, University of Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Schmitzer+AR%22">Schmitzer AR</searchLink>; Department of Chemistry, University of Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Ferbeyre+G%22">Ferbeyre G</searchLink>; Department of Biochemistry and Molecular Medicine, CR-CHUM and Montreal Cancer Institute, University of Montreal, Montreal, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101579614%22">ELife</searchLink> [Elife] 2026 May 15; Vol. 13. <i>Date of Electronic Publication: </i>2026 May 15.
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