Synergistic attenuation of Aeromonas dhakensis virulence by dual deletion of PhoBR and KdpE two-component systems and its protective immunity in zebrafish.
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| Title: | Synergistic attenuation of Aeromonas dhakensis virulence by dual deletion of PhoBR and KdpE two-component systems and its protective immunity in zebrafish. |
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| Authors: | Li X; Lab of Microbiological Engineering (Infection and Immunity), School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, 570228, Hainan, China.; Hainan International One Health Institute, Hainan University, Haikou, 570228, Hainan, China., Wu Y; Lab of Microbiological Engineering (Infection and Immunity), School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, 570228, Hainan, China.; Hainan International One Health Institute, Hainan University, Haikou, 570228, Hainan, China., Wang M; Lab of Microbiological Engineering (Infection and Immunity), School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, 570228, Hainan, China.; Hainan International One Health Institute, Hainan University, Haikou, 570228, Hainan, China., Li R; Lab of Microbiological Engineering (Infection and Immunity), School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, 570228, Hainan, China.; Hainan International One Health Institute, Hainan University, Haikou, 570228, Hainan, China., Gao H; Dongfang Hewangxin Breeding Co., Ltd, Dongfang, 572600, China., Yang C; Lab of Microbiological Engineering (Infection and Immunity), School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, 570228, Hainan, China.; Hainan International One Health Institute, Hainan University, Haikou, 570228, Hainan, China., Yi A; Lab of Microbiological Engineering (Infection and Immunity), School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, 570228, Hainan, China.; Hainan International One Health Institute, Hainan University, Haikou, 570228, Hainan, China., Wang X; Lab of Microbiological Engineering (Infection and Immunity), School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, 570228, Hainan, China.; Hainan International One Health Institute, Hainan University, Haikou, 570228, Hainan, China., Ye S; Lab of Microbiological Engineering (Infection and Immunity), School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, 570228, Hainan, China.; Hainan International One Health Institute, Hainan University, Haikou, 570228, Hainan, China., Guo G; School of Chemical Engineering and Technology, Hainan University, Haikou, 570228, China., Fan L; Lab of Microbiological Engineering (Infection and Immunity), School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, 570228, Hainan, China.; Hainan International One Health Institute, Hainan University, Haikou, 570228, Hainan, China., Yang N; Lab of Microbiological Engineering (Infection and Immunity), School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, 570228, Hainan, China.; Hainan International One Health Institute, Hainan University, Haikou, 570228, Hainan, China., Zeng J; Lab of Microbiological Engineering (Infection and Immunity), School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, 570228, Hainan, China.; Hainan International One Health Institute, Hainan University, Haikou, 570228, Hainan, China., Zheng J; Lab of Microbiological Engineering (Infection and Immunity), School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, 570228, Hainan, China. zhenglab909@163.com.; Hainan International One Health Institute, Hainan University, Haikou, 570228, Hainan, China. zhenglab909@163.com. |
| Source: | Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2026 May 15; Vol. 110 (1). Date of Electronic Publication: 2026 May 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer International Country of Publication: Germany NLM ID: 8406612 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0614 (Electronic) Linking ISSN: 01757598 NLM ISO Abbreviation: Appl Microbiol Biotechnol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-0614 |
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| DOI: | 10.1007/s00253-026-13859-1 |
