Disrupting the CBFβ-SMMHC-RUNX1 oncogenic protein-protein interaction in inv(16) AML: from fusion biology to targeted therapy.
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| Title: | Disrupting the CBFβ-SMMHC-RUNX1 oncogenic protein-protein interaction in inv(16) AML: from fusion biology to targeted therapy. |
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| Authors: | Kamel EM; Chemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef, 62514, Egypt., Khadrawy SM; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia., Ali MAM; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia., Ahmed NA; Physiology Division, Zoology Department, Faculty of Science, Beni-Suef University, P. O. Box 62521, Beni-Suef, Egypt. drnohascience@science.bsu.edu.eg., Alkhedhairi S; Department of Medical Biosciences, College of Veterinary Medicine, Qassim University, P. O. Box 6622, Buraydah, 51452, Saudi Arabia., Alkhayl FFA; Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, 51452, Saudi Arabia., Lamsabhi AM; Departamento de Química and Institute for advanced research in chemical Science (IAdChem), Facultad de Ciencias, Universidad Autónoma de Madrid, Módulo 13, Madrid, 28049, Spain. |
| Source: | Discover oncology [Discov Oncol] 2026 May 16; Vol. 17 (1). Date of Electronic Publication: 2026 May 16. |
| Publication Type: | Journal Article; Review |
| Journal Info: | Publisher: Springer Country of Publication: United States NLM ID: 101775142 Publication Model: Electronic Cited Medium: Internet ISSN: 2730-6011 (Electronic) Linking ISSN: 27306011 NLM ISO Abbreviation: Discov Oncol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2730-6011 |
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| DOI: | 10.1007/s12672-026-05066-1 |
