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Disrupting the CBFβ-SMMHC-RUNX1 oncogenic protein-protein interaction in inv(16) AML: from fusion biology to targeted therapy.

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Title: Disrupting the CBFβ-SMMHC-RUNX1 oncogenic protein-protein interaction in inv(16) AML: from fusion biology to targeted therapy.
Authors: Kamel EM; Chemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef, 62514, Egypt., Khadrawy SM; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia., Ali MAM; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia., Ahmed NA; Physiology Division, Zoology Department, Faculty of Science, Beni-Suef University, P. O. Box 62521, Beni-Suef, Egypt. drnohascience@science.bsu.edu.eg., Alkhedhairi S; Department of Medical Biosciences, College of Veterinary Medicine, Qassim University, P. O. Box 6622, Buraydah, 51452, Saudi Arabia., Alkhayl FFA; Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, 51452, Saudi Arabia., Lamsabhi AM; Departamento de Química and Institute for advanced research in chemical Science (IAdChem), Facultad de Ciencias, Universidad Autónoma de Madrid, Módulo 13, Madrid, 28049, Spain.
Source: Discover oncology [Discov Oncol] 2026 May 16; Vol. 17 (1). Date of Electronic Publication: 2026 May 16.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101775142 Publication Model: Electronic Cited Medium: Internet ISSN: 2730-6011 (Electronic) Linking ISSN: 27306011 NLM ISO Abbreviation: Discov Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Disrupting the CBFβ-SMMHC-RUNX1 oncogenic protein-protein interaction in inv(16) AML: from fusion biology to targeted therapy.
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  Data: <searchLink fieldCode="AU" term="%22Kamel+EM%22">Kamel EM</searchLink>; Chemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef, 62514, Egypt.<br /><searchLink fieldCode="AU" term="%22Khadrawy+SM%22">Khadrawy SM</searchLink>; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ali+MAM%22">Ali MAM</searchLink>; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ahmed+NA%22">Ahmed NA</searchLink>; Physiology Division, Zoology Department, Faculty of Science, Beni-Suef University, P. O. Box 62521, Beni-Suef, Egypt. drnohascience@science.bsu.edu.eg.<br /><searchLink fieldCode="AU" term="%22Alkhedhairi+S%22">Alkhedhairi S</searchLink>; Department of Medical Biosciences, College of Veterinary Medicine, Qassim University, P. O. Box 6622, Buraydah, 51452, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alkhayl+FFA%22">Alkhayl FFA</searchLink>; Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, 51452, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Lamsabhi+AM%22">Lamsabhi AM</searchLink>; Departamento de Química and Institute for advanced research in chemical Science (IAdChem), Facultad de Ciencias, Universidad Autónoma de Madrid, Módulo 13, Madrid, 28049, Spain.
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  Data: <searchLink fieldCode="JN" term="%22101775142%22">Discover oncology</searchLink> [Discov Oncol] 2026 May 16; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 May 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101775142 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2730-6011 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2227306011%22">27306011 </searchLink><i>NLM ISO Abbreviation: </i>Discov Oncol <i>Subsets: </i>PubMed not MEDLINE
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      – TitleFull: Disrupting the CBFβ-SMMHC-RUNX1 oncogenic protein-protein interaction in inv(16) AML: from fusion biology to targeted therapy.
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              Text: 2026 May 16
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