More than an attachment module: covalent inhibitor warheads influence BTK dynamics and function.
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| Title: | More than an attachment module: covalent inhibitor warheads influence BTK dynamics and function. |
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| Authors: | Joseph RE; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA., Britton RG; Division of Cancer Sciences, Cancer Research Centre, College of Life Sciences, University of Leicester, Leicester LE1 9HN, UK., Lin DY; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA., Roche J; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA., Purslow JA; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA., Fulton DB; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA., Fukasem P; Department of Biomedical Engineering, School of Engineering, King Mongkut's Institute of Technology, Ladkrabang, Bangkok 10520, Thailand., Gleeson MP; Department of Biomedical Engineering, School of Engineering, King Mongkut's Institute of Technology, Ladkrabang, Bangkok 10520, Thailand., Dyer MJS; The Ernest and Helen Scott Haematological Research Institute, Leicester Cancer Research Centre, College of Life Sciences, University of Leicester, Leicester LE1 9HN, UK., Wales TE; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA., Andreotti AH; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2026 May 08. Date of Electronic Publication: 2026 May 08. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42146433 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: More than an attachment module: covalent inhibitor warheads influence BTK dynamics and function. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Joseph+RE%22">Joseph RE</searchLink>; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA.<br /><searchLink fieldCode="AU" term="%22Britton+RG%22">Britton RG</searchLink>; Division of Cancer Sciences, Cancer Research Centre, College of Life Sciences, University of Leicester, Leicester LE1 9HN, UK.<br /><searchLink fieldCode="AU" term="%22Lin+DY%22">Lin DY</searchLink>; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA.<br /><searchLink fieldCode="AU" term="%22Roche+J%22">Roche J</searchLink>; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA.<br /><searchLink fieldCode="AU" term="%22Purslow+JA%22">Purslow JA</searchLink>; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA.<br /><searchLink fieldCode="AU" term="%22Fulton+DB%22">Fulton DB</searchLink>; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA.<br /><searchLink fieldCode="AU" term="%22Fukasem+P%22">Fukasem P</searchLink>; Department of Biomedical Engineering, School of Engineering, King Mongkut's Institute of Technology, Ladkrabang, Bangkok 10520, Thailand.<br /><searchLink fieldCode="AU" term="%22Gleeson+MP%22">Gleeson MP</searchLink>; Department of Biomedical Engineering, School of Engineering, King Mongkut's Institute of Technology, Ladkrabang, Bangkok 10520, Thailand.<br /><searchLink fieldCode="AU" term="%22Dyer+MJS%22">Dyer MJS</searchLink>; The Ernest and Helen Scott Haematological Research Institute, Leicester Cancer Research Centre, College of Life Sciences, University of Leicester, Leicester LE1 9HN, UK.<br /><searchLink fieldCode="AU" term="%22Wales+TE%22">Wales TE</searchLink>; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Andreotti+AH%22">Andreotti AH</searchLink>; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 May 08. <i>Date of Electronic Publication: </i>2026 May 08. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Preprint – Name: TitleSource Label: Journal Info Group: Src Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42146433 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.64898/2026.05.07.723540 Languages: – Code: eng Text: English Titles: – TitleFull: More than an attachment module: covalent inhibitor warheads influence BTK dynamics and function. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Joseph RE – PersonEntity: Name: NameFull: Britton RG – PersonEntity: Name: NameFull: Lin DY – PersonEntity: Name: NameFull: Roche J – PersonEntity: Name: NameFull: Purslow JA – PersonEntity: Name: NameFull: Fulton DB – PersonEntity: Name: NameFull: Fukasem P – PersonEntity: Name: NameFull: Gleeson MP – PersonEntity: Name: NameFull: Dyer MJS – PersonEntity: Name: NameFull: Wales TE – PersonEntity: Name: NameFull: Andreotti AH IsPartOfRelationships: – BibEntity: Dates: – D: 08 M: 05 Text: 2026 May 08 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2692-8205 Titles: – TitleFull: BioRxiv : the preprint server for biology Type: main |
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