Low-Dose Buprenorphine Following Ketamine Treatment for Suicidal Ideation in Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial.

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Title: Low-Dose Buprenorphine Following Ketamine Treatment for Suicidal Ideation in Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial.
Authors: Tucciarone JM; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA., Bandeira ID; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA., Blasey C; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA.; Palo Alto University, Palo Alto, CA., Kratter IH; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA., Ehrie J; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA., Keller J; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA., Pankow H; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA., Chang M; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA., Hawkins J; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA., Evers AG; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA.; Palo Alto University, Palo Alto, CA., Bernert R; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA., DeBattista C; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA., Truong H; Mariner Pharmacy, San Mateo, CA., Rodriguez CI; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA., Heifets BD; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA.; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA., Schatzberg AF; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA.
Source: The American journal of psychiatry [Am J Psychiatry] 2026 Jun 01; Vol. 183 (6), pp. 409-419. Date of Electronic Publication: 2026 May 19.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: American Psychiatric Association Country of Publication: United States NLM ID: 0370512 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-7228 (Electronic) Linking ISSN: 0002953X NLM ISO Abbreviation: Am J Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1535-7228
DOI:10.1176/appi.ajp.20250840