ERBB4 activation prevents microvascular dysfunction in a large animal model of hypertensive heart disease.
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| Title: | ERBB4 activation prevents microvascular dysfunction in a large animal model of hypertensive heart disease. |
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| Authors: | Tubeeckx MRL; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium., Bringmans T; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.; Department of Cardiology, University Hospital Antwerp, Antwerp, Belgium., Goovaerts B; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium., Van den Bogaert S; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium., Grootaert MOJ; Centre for Molecular and Vascular Biology, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium., Jones EAV; Centre for Molecular and Vascular Biology, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium., Korpisalo P; Heart Center, Kuopio University Hospital, Kuopio, Finland., Juusola G; Heart Center, Kuopio University Hospital, Kuopio, Finland.; A.I. Virtanen Institute, University of Eastern Finland, Kuopio, Finland., Wirth G; Heart Center, Kuopio University Hospital, Kuopio, Finland.; A.I. Virtanen Institute, University of Eastern Finland, Kuopio, Finland., Murphy SL; Salubris Biotherapeutics, Inc., Gaithersburg, Maryland, United States., Heidbuchel H; Department of Cardiology, University Hospital Antwerp, Antwerp, Belgium.; Research Group Cardiovascular Diseases, GENCOR, University of Antwerp, Antwerp, Belgium., De Keulenaer GW; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.; Department of Cardiology, ZNA Middelheim, Antwerp, Belgium., Segers VFM; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.; Department of Cardiology, University Hospital Antwerp, Antwerp, Belgium. |
| Source: | American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2026 Jun 01; Vol. 330 (6), pp. H2025-H2035. Date of Electronic Publication: 2026 May 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901228 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1539 (Electronic) Linking ISSN: 03636135 NLM ISO Abbreviation: Am J Physiol Heart Circ Physiol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1522-1539 |
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| DOI: | 10.1152/ajpheart.00303.2025 |
