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Endothelium- selective overexpression of p25 results in impaired smooth muscle-dependent vascular function, altered sGC-dependent pathway, and vascular remodeling.

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Title: Endothelium- selective overexpression of p25 results in impaired smooth muscle-dependent vascular function, altered sGC-dependent pathway, and vascular remodeling.
Authors: Sternak M; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, Poland. Electronic address: magdalena.sternak@jcet.eu., Wang P; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China; Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Bar A; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, Poland., Kieronska-Rudek A; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, Poland., Kurylowicz Z; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, Poland., Jasztal A; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, Poland., Kij A; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, Poland., Wang Y; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China; Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China. Electronic address: yuwanghk@hku.hk., Chlopicki S; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, Poland; Medical College, Chair of Pharmacology, Jagiellonian University, Grzegorzecka 16, Krakow, Poland. Electronic address: stefan.chlopicki@jcet.eu.
Source: Vascular pharmacology [Vascul Pharmacol] 2026 Jun; Vol. 163, pp. 107653. Date of Electronic Publication: 2026 May 18.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 101130615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3649 (Electronic) Linking ISSN: 15371891 NLM ISO Abbreviation: Vascul Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-3649
DOI:10.1016/j.vph.2026.107653