Gene-gene interactions between a LMNA variant and common polymorphisms drive early-onset atrial fibrillation.
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| Title: | Gene-gene interactions between a LMNA variant and common polymorphisms drive early-onset atrial fibrillation. |
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| Authors: | Owais A; Department of Medicine, Division of Cardiology, University of Illinois Chicago, Chicago, IL, USA., Chen H; Department of Medicine, Division of Cardiology, University of Illinois Chicago, Chicago, IL, USA., Farooq H; Center for Bioinformatics and Quantitative Biology, University of Illinois Chicago, Chicago, IL, USA.; Richard and Loan Hill Department of Biomedical Engineering, University of Illinois Chicago, Chicago, IL, USA., Thami PK; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, Imperial College London, London, UK., McGurk KA; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, Imperial College London, London, UK.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Powell GJ; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, Imperial College London, London, UK., DeSantiago J; Department of Medicine, Division of Cardiology, University of Illinois Chicago, Chicago, IL, USA., Abbas T; Department of Biochemistry & Molecular Genetics, University of Illinois Chicago, Chicago, IL, USA., Sridhar A; Department of Medicine, Division of Cardiology, University of Illinois Chicago, Chicago, IL, USA., Pavel A; Department of Medicine, Division of Cardiology, University of Illinois Chicago, Chicago, IL, USA., Webster G; Section of Electrophysiology, Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, IL, USA., Merrill B; Department of Biochemistry & Molecular Genetics, University of Illinois Chicago, Chicago, IL, USA., Ware JS; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, Imperial College London, London, UK.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Ng FS; National Heart and Lung Institute, Imperial College London, London, UK., Darbar D; Department of Medicine, Penn State College of Medicine, Hershey, PA, USA. ddarbar@pennstatehealth.psu.edu. |
| Source: | Nature communications [Nat Commun] 2026 May 19; Vol. 17 (1). Date of Electronic Publication: 2026 May 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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