Human cathelicidin peptide LL-37 compacts nucleic acids and alters neutrophil extracellular trap structure.

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Title: Human cathelicidin peptide LL-37 compacts nucleic acids and alters neutrophil extracellular trap structure.
Authors: Zielke C; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA, 94305, USA., Rad B; Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Nielsen JE; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA, 94305, USA.; Department of Science and Environment, Roskilde University, Roskilde, 4000, Denmark.; Department of Pharmacy, Section for Pharmaceutics and Social Pharmacy, University of Oslo, Oslo, 0371, Norway., Li J; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA, 94305, USA., Pimcharoen S; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA, 94305, USA., Sawant M; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA, 94305, USA.; ChEM-H Institute, Stanford University, Stanford, CA, 94305, USA.; Chan Zuckerberg Biohub, San Francisco, CA, 94158, USA., Kamayirese S; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA, 94305, USA., Lin JS; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA, 94305, USA., Thiam HR; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA, 94305, USA.; ChEM-H Institute, Stanford University, Stanford, CA, 94305, USA.; Chan Zuckerberg Biohub, San Francisco, CA, 94158, USA., Barron AE; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA, 94305, USA. aebarron@stanford.edu.
Source: Scientific reports [Sci Rep] 2026 May 19; Vol. 16 (1). Date of Electronic Publication: 2026 May 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-026-48091-4