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Tetrameric assembly disruption impairs CXCL4 chaperon ability for DNA and type I interferon immune amplification.

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Title: Tetrameric assembly disruption impairs CXCL4 chaperon ability for DNA and type I interferon immune amplification.
Authors: Ocone G; Istituto Superiore di Sanità, National center for Global Health, Roma, Italy., Mennella A; Istituto Superiore di Sanità, National center for Global Health, Roma, Italy., Pietraforte I; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy., Palazzo R; Istituto Superiore di Sanità, National center for Global Health, Roma, Italy., Spinelli FR; Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Roma, Italy., Gaddini L; Istituto Superiore di Sanità, National Center for drug research and evaluation, Roma, Italy., Stefanantoni K; Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Roma, Italy., Riccieri V; Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Roma, Italy., Lee EY; Department of Bioengineering, Department of Chemistry & Biochemistry, and California, NanoSystems Institute, University of California, Los Angeles, CA, USA.; Department of Dermatology, University of California, San Francisco, CA, USA., Wong GCL; Department of Bioengineering, Department of Chemistry & Biochemistry, and California, NanoSystems Institute, University of California, Los Angeles, CA, USA., Lande R; Istituto Superiore di Sanità, National center for Global Health, Roma, Italy., Frasca L; Istituto Superiore di Sanità, National center for Global Health, Roma, Italy. loredana.frasca@iss.it.
Source: Communications biology [Commun Biol] 2026 May 19. Date of Electronic Publication: 2026 May 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
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  Data: Tetrameric assembly disruption impairs CXCL4 chaperon ability for DNA and type I interferon immune amplification.
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  Data: <searchLink fieldCode="AU" term="%22Ocone+G%22">Ocone G</searchLink>; Istituto Superiore di Sanità, National center for Global Health, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Mennella+A%22">Mennella A</searchLink>; Istituto Superiore di Sanità, National center for Global Health, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Pietraforte+I%22">Pietraforte I</searchLink>; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Palazzo+R%22">Palazzo R</searchLink>; Istituto Superiore di Sanità, National center for Global Health, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Spinelli+FR%22">Spinelli FR</searchLink>; Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Gaddini+L%22">Gaddini L</searchLink>; Istituto Superiore di Sanità, National Center for drug research and evaluation, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Stefanantoni+K%22">Stefanantoni K</searchLink>; Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Riccieri+V%22">Riccieri V</searchLink>; Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Lee+EY%22">Lee EY</searchLink>; Department of Bioengineering, Department of Chemistry & Biochemistry, and California, NanoSystems Institute, University of California, Los Angeles, CA, USA.; Department of Dermatology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wong+GCL%22">Wong GCL</searchLink>; Department of Bioengineering, Department of Chemistry & Biochemistry, and California, NanoSystems Institute, University of California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lande+R%22">Lande R</searchLink>; Istituto Superiore di Sanità, National center for Global Health, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Frasca+L%22">Frasca L</searchLink>; Istituto Superiore di Sanità, National center for Global Health, Roma, Italy. loredana.frasca@iss.it.
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  Data: <searchLink fieldCode="JN" term="%22101719179%22">Communications biology</searchLink> [Commun Biol] 2026 May 19. <i>Date of Electronic Publication: </i>2026 May 19.
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              Text: 2026 May 19
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