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Reproductive toxicity induced by a repeated 28-day oral exposure to a commercial mixture of the herbicides S-metolachlor and flumioxazin in male rats.

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Title: Reproductive toxicity induced by a repeated 28-day oral exposure to a commercial mixture of the herbicides S-metolachlor and flumioxazin in male rats.
Authors: Carvalho RK; Laboratory of Physiology and Pharmacology of Reproduction, Department of Pharmacology, Federal University of Goiás, Goiânia, GO, Brazil., Reis DS; Laboratory of Pharmacology and Toxicology of Natural and Synthetic Products, State University of Goiás, Anápolis, GO, Brazil., Santiago ALG; Laboratory of Pharmacology and Toxicology of Natural and Synthetic Products, State University of Goiás, Anápolis, GO, Brazil., Rodrigues BM; Laboratory of Pharmacology and Toxicology of Natural and Synthetic Products, State University of Goiás, Anápolis, GO, Brazil., Leite JA; Institute of Biological Sciences, Department of Pharmacology, Federal University of Goiás, Goiânia, GO, Brazil., Júnior WD; Laboratory of Physiology and Toxicological Biochemistry, State University of Goiás, Ceres, GO, Brazil., Damin V; School of Agronomy, Federal University of Goiás, Goiânia, GO, Brazil., Andersen ML; Department of Psychobiology, Federal University of São Paulo, São Paulo, SP, Brazil., Souza MR; Department of Psychobiology, Federal University of São Paulo, São Paulo, SP, Brazil., Ghedini PC; Laboratory of Molecular and Biochemistry Pharmacology, Department of Pharmacology, Federal University of Goiás, Goiânia, GO, Brazil., Campos HM; Laboratory of Molecular and Biochemistry Pharmacology, Department of Pharmacology, Federal University of Goiás, Goiânia, GO, Brazil., Silva DM; Laboratory of Mutagenesis, Department of Genetics, Federal University of Goiás, Goiânia, GO, Brazil., Amaral VCS; Laboratory of Pharmacology and Toxicology of Natural and Synthetic Products, State University of Goiás, Anápolis, GO, Brazil., Almeida LM; Laboratory of Biotechnology, State University of Goiás, Anápolis, GO, Brazil., Mazaro-Costa R; Laboratory of Physiology and Pharmacology of Reproduction, Department of Pharmacology, Federal University of Goiás, Goiânia, GO, Brazil. Electronic address: mazaro@ufg.br.
Source: Chemico-biological interactions [Chem Biol Interact] 2026 Jul 25; Vol. 435, pp. 112151. Date of Electronic Publication: 2026 May 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Reproductive toxicity induced by a repeated 28-day oral exposure to a commercial mixture of the herbicides S-metolachlor and flumioxazin in male rats.
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  Data: <searchLink fieldCode="AU" term="%22Carvalho+RK%22">Carvalho RK</searchLink>; Laboratory of Physiology and Pharmacology of Reproduction, Department of Pharmacology, Federal University of Goiás, Goiânia, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Reis+DS%22">Reis DS</searchLink>; Laboratory of Pharmacology and Toxicology of Natural and Synthetic Products, State University of Goiás, Anápolis, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Santiago+ALG%22">Santiago ALG</searchLink>; Laboratory of Pharmacology and Toxicology of Natural and Synthetic Products, State University of Goiás, Anápolis, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Rodrigues+BM%22">Rodrigues BM</searchLink>; Laboratory of Pharmacology and Toxicology of Natural and Synthetic Products, State University of Goiás, Anápolis, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Leite+JA%22">Leite JA</searchLink>; Institute of Biological Sciences, Department of Pharmacology, Federal University of Goiás, Goiânia, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Júnior+WD%22">Júnior WD</searchLink>; Laboratory of Physiology and Toxicological Biochemistry, State University of Goiás, Ceres, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Damin+V%22">Damin V</searchLink>; School of Agronomy, Federal University of Goiás, Goiânia, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Andersen+ML%22">Andersen ML</searchLink>; Department of Psychobiology, Federal University of São Paulo, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Souza+MR%22">Souza MR</searchLink>; Department of Psychobiology, Federal University of São Paulo, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Ghedini+PC%22">Ghedini PC</searchLink>; Laboratory of Molecular and Biochemistry Pharmacology, Department of Pharmacology, Federal University of Goiás, Goiânia, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Campos+HM%22">Campos HM</searchLink>; Laboratory of Molecular and Biochemistry Pharmacology, Department of Pharmacology, Federal University of Goiás, Goiânia, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Silva+DM%22">Silva DM</searchLink>; Laboratory of Mutagenesis, Department of Genetics, Federal University of Goiás, Goiânia, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Amaral+VCS%22">Amaral VCS</searchLink>; Laboratory of Pharmacology and Toxicology of Natural and Synthetic Products, State University of Goiás, Anápolis, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Almeida+LM%22">Almeida LM</searchLink>; Laboratory of Biotechnology, State University of Goiás, Anápolis, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Mazaro-Costa+R%22">Mazaro-Costa R</searchLink>; Laboratory of Physiology and Pharmacology of Reproduction, Department of Pharmacology, Federal University of Goiás, Goiânia, GO, Brazil. Electronic address: mazaro@ufg.br.
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  Data: <searchLink fieldCode="JN" term="%220227276%22">Chemico-biological interactions</searchLink> [Chem Biol Interact] 2026 Jul 25; Vol. 435, pp. 112151. <i>Date of Electronic Publication: </i>2026 May 19.
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