Parenteral neonatal priming followed by heterologous mucosal booster favors IgM+ memory B cell induction over systemic plasma cell differentiation.

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Title: Parenteral neonatal priming followed by heterologous mucosal booster favors IgM+ memory B cell induction over systemic plasma cell differentiation.
Authors: Foroutan Pajoohian P; Faculty of Medicine, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Immunology, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland., Aradottir Pind AA; Faculty of Medicine, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Immunology, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland., Molina Estupiñan JL; Faculty of Medicine, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Immunology, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland., Christensen D; Center for Vaccine Research, Statens Serum Institut, Copenhagen, Denmark., Pedersen GK; Center for Vaccine Research, Statens Serum Institut, Copenhagen, Denmark., Olafsdottir TA; Faculty of Medicine, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Jonsdottir I; Faculty of Medicine, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Bjarnarson SP; Faculty of Medicine, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Immunology, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
Source: Frontiers in immunology [Front Immunol] 2026 May 05; Vol. 17, pp. 1792155. Date of Electronic Publication: 2026 May 05 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1792155