Hypoactivity, abnormal development of dendrites relevant to impaired synaptic transmission of calretinin-expressing interneurons in the medial prefrontal cortex underlies social deficits of mouse model in autism.

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Title: Hypoactivity, abnormal development of dendrites relevant to impaired synaptic transmission of calretinin-expressing interneurons in the medial prefrontal cortex underlies social deficits of mouse model in autism.
Authors: Chen M; Henan Key Laboratory of Genetic and Developmental Disorders, Henan Children's Neurodevelopment Engineering Research Center, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou, 450018, China., Zhao K; Henan Key Laboratory of Genetic and Developmental Disorders, Henan Children's Neurodevelopment Engineering Research Center, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou, 450018, China., Gao C; Department of Rehabilitation, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China., Mei D; Department of Neurology, Children's Hospital of Soochow University, Suzhou, China., Shi S; Department of Image, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China., Wang L; Department of Neurology, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China., Sun L; Shanghai Institute of Microsystem and Information Technology, Shanghai, China., Guo J; Department of Pathology, School of Basic Medical Sciences, Yantai Campus of Binzhou Medical University, Yantai, China., Bin G; School of traditional Chinese medicine, Ningxia Medical University, Xingqing, Ningxia, China., Zhao S; Henan Key Laboratory of Genetic and Developmental Disorders, Henan Children's Neurodevelopment Engineering Research Center, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou, 450018, China., Yan X; Henan Key Laboratory of Genetic and Developmental Disorders, Henan Children's Neurodevelopment Engineering Research Center, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou, 450018, China., He M; Institutes of Brain Science, State Key laboratory of medical neurobiology and MOE Frontiers center for Brain Science, department of neurobiology, Zhongshan hospital, Fudan University, Shanghai, China. hem@fudan.edu.cn., Zhang Y; Henan Key Laboratory of Genetic and Developmental Disorders, Henan Children's Neurodevelopment Engineering Research Center, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou, 450018, China. syek@163.com., Wang X; Henan Key Laboratory of Genetic and Developmental Disorders, Henan Children's Neurodevelopment Engineering Research Center, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou, 450018, China. xiaonawang2015@163.com.
Source: Translational psychiatry [Transl Psychiatry] 2026 May 21; Vol. 16 (1). Date of Electronic Publication: 2026 May 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
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  Data: Hypoactivity, abnormal development of dendrites relevant to impaired synaptic transmission of calretinin-expressing interneurons in the medial prefrontal cortex underlies social deficits of mouse model in autism.
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  Data: <searchLink fieldCode="AU" term="%22Chen+M%22">Chen M</searchLink>; Henan Key Laboratory of Genetic and Developmental Disorders, Henan Children's Neurodevelopment Engineering Research Center, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou, 450018, China.<br /><searchLink fieldCode="AU" term="%22Zhao+K%22">Zhao K</searchLink>; Henan Key Laboratory of Genetic and Developmental Disorders, Henan Children's Neurodevelopment Engineering Research Center, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou, 450018, China.<br /><searchLink fieldCode="AU" term="%22Gao+C%22">Gao C</searchLink>; Department of Rehabilitation, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Mei+D%22">Mei D</searchLink>; Department of Neurology, Children's Hospital of Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Shi+S%22">Shi S</searchLink>; Department of Image, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Neurology, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Sun+L%22">Sun L</searchLink>; Shanghai Institute of Microsystem and Information Technology, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Guo+J%22">Guo J</searchLink>; Department of Pathology, School of Basic Medical Sciences, Yantai Campus of Binzhou Medical University, Yantai, China.<br /><searchLink fieldCode="AU" term="%22Bin+G%22">Bin G</searchLink>; School of traditional Chinese medicine, Ningxia Medical University, Xingqing, Ningxia, China.<br /><searchLink fieldCode="AU" term="%22Zhao+S%22">Zhao S</searchLink>; Henan Key Laboratory of Genetic and Developmental Disorders, Henan Children's Neurodevelopment Engineering Research Center, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou, 450018, China.<br /><searchLink fieldCode="AU" term="%22Yan+X%22">Yan X</searchLink>; Henan Key Laboratory of Genetic and Developmental Disorders, Henan Children's Neurodevelopment Engineering Research Center, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou, 450018, China.<br /><searchLink fieldCode="AU" term="%22He+M%22">He M</searchLink>; Institutes of Brain Science, State Key laboratory of medical neurobiology and MOE Frontiers center for Brain Science, department of neurobiology, Zhongshan hospital, Fudan University, Shanghai, China. hem@fudan.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Henan Key Laboratory of Genetic and Developmental Disorders, Henan Children's Neurodevelopment Engineering Research Center, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou, 450018, China. syek@163.com.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Henan Key Laboratory of Genetic and Developmental Disorders, Henan Children's Neurodevelopment Engineering Research Center, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou, 450018, China. xiaonawang2015@163.com.
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  Data: <searchLink fieldCode="JN" term="%22101562664%22">Translational psychiatry</searchLink> [Transl Psychiatry] 2026 May 21; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 May 21.
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