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Retinal macrophage-like cell activation and ganglion cell layer thinning are associated with disability and MRI lesion burden in multiple sclerosis.

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Title: Retinal macrophage-like cell activation and ganglion cell layer thinning are associated with disability and MRI lesion burden in multiple sclerosis.
Authors: Pichi F; University of Toronto, Department of Ophthalmology and Vision Sciences, Toronto, Canada.; Eye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Jimenez YP; Eye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Belletti M; IRCSS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Alsuwaidi A; Radiology Department, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Alawadhi F; Radiology Department, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Lee G; Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Neri P; Eye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Mifsud V; Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Jacob A; Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Benedetti B; Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Carreño E; Hospital Universitario la Paz, Madrid, Spain.
Source: PloS one [PLoS One] 2026 May 22; Vol. 21 (5), pp. e0349679. Date of Electronic Publication: 2026 May 22 (Print Publication: 2026).
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0349679