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Retinal macrophage-like cell activation and ganglion cell layer thinning are associated with disability and MRI lesion burden in multiple sclerosis.

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Title: Retinal macrophage-like cell activation and ganglion cell layer thinning are associated with disability and MRI lesion burden in multiple sclerosis.
Authors: Pichi F; University of Toronto, Department of Ophthalmology and Vision Sciences, Toronto, Canada.; Eye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Jimenez YP; Eye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Belletti M; IRCSS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Alsuwaidi A; Radiology Department, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Alawadhi F; Radiology Department, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Lee G; Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Neri P; Eye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Mifsud V; Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Jacob A; Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Benedetti B; Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Carreño E; Hospital Universitario la Paz, Madrid, Spain.
Source: PloS one [PLoS One] 2026 May 22; Vol. 21 (5), pp. e0349679. Date of Electronic Publication: 2026 May 22 (Print Publication: 2026).
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Retinal macrophage-like cell activation and ganglion cell layer thinning are associated with disability and MRI lesion burden in multiple sclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Pichi+F%22">Pichi F</searchLink>; University of Toronto, Department of Ophthalmology and Vision Sciences, Toronto, Canada.; Eye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Jimenez+YP%22">Jimenez YP</searchLink>; Eye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Belletti+M%22">Belletti M</searchLink>; IRCSS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Alsuwaidi+A%22">Alsuwaidi A</searchLink>; Radiology Department, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Alawadhi+F%22">Alawadhi F</searchLink>; Radiology Department, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Lee+G%22">Lee G</searchLink>; Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Neri+P%22">Neri P</searchLink>; Eye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Mifsud+V%22">Mifsud V</searchLink>; Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Jacob+A%22">Jacob A</searchLink>; Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Benedetti+B%22">Benedetti B</searchLink>; Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Carreño+E%22">Carreño E</searchLink>; Hospital Universitario la Paz, Madrid, Spain.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2026 May 22; Vol. 21 (5), pp. e0349679. <i>Date of Electronic Publication: </i>2026 May 22 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101285081 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1932-6203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219326203%22">19326203 </searchLink><i>NLM ISO Abbreviation: </i>PLoS One <i>Subsets: </i>MEDLINE
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