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A Randomized, Double-Blind, Pilot Study of N-Acetylcysteine for Motor and Cognitive Symptoms in Youth With Neurofibromatosis Type 1.

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Title: A Randomized, Double-Blind, Pilot Study of N-Acetylcysteine for Motor and Cognitive Symptoms in Youth With Neurofibromatosis Type 1.
Authors: Gilbert DL; Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio. Electronic address: Donald.gilbert@cchmc.org., Aschbacher-Smith LE; Division of Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Migneault KY; Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Huddleston DA; Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Cecil KM; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Beebe DW; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Zhang B; Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Ratner N; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital, Cincinnati, Ohio., Prada CE; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Source: Pediatric neurology [Pediatr Neurol] 2026 Jul; Vol. 180, pp. 129-137. Date of Electronic Publication: 2026 May 05.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Science Publishing Country of Publication: United States NLM ID: 8508183 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5150 (Electronic) Linking ISSN: 08878994 NLM ISO Abbreviation: Pediatr Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Gilbert+DL%22">Gilbert DL</searchLink>; Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio. Electronic address: Donald.gilbert@cchmc.org.<br /><searchLink fieldCode="AU" term="%22Aschbacher-Smith+LE%22">Aschbacher-Smith LE</searchLink>; Division of Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Migneault+KY%22">Migneault KY</searchLink>; Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Huddleston+DA%22">Huddleston DA</searchLink>; Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Cecil+KM%22">Cecil KM</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Beebe+DW%22">Beebe DW</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Zhang+B%22">Zhang B</searchLink>; Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Ratner+N%22">Ratner N</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Prada+CE%22">Prada CE</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
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      – Type: doi
        Value: 10.1016/j.pediatrneurol.2026.04.024
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      – Code: eng
        Text: English
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        StartPage: 129
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      – TitleFull: A Randomized, Double-Blind, Pilot Study of N-Acetylcysteine for Motor and Cognitive Symptoms in Youth With Neurofibromatosis Type 1.
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              Text: 2026 Jul
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              Y: 2026
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