Distinct proteomic signatures of urinary extracellular vesicles link to albuminuria and treatment responses in diabetic kidney disease.

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Title: Distinct proteomic signatures of urinary extracellular vesicles link to albuminuria and treatment responses in diabetic kidney disease.
Authors: van Heugten MH; Department of Internal Medicine, Division of Nephrology and Transplantation, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands., Beckmann SB; Department of Internal Medicine, Division of Nephrology and Transplantation, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands., Salib M; Department of Internal Medicine, Division of Nephrology and Transplantation, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands., Curovic VR; Steno Diabetes Center Copenhagen, Herlev, Denmark., Beernink JM; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, Groningen, the Netherlands., Faivre A; Department of Medicine and Cell Physiology and Metabolism, University of Geneva, Geneva, Switzerland., Laverman GD; Department of Internal Medicine, ZiekenhuisGroep Twente, Almelo, the Netherlands., Wu Q; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Bjornstad P; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, and Division of Endocrinology, Department of Pediatrics, University of Washington, Seattle, Washington, USA., Hall AM; Institute of Anatomy and Zürich Kidney Center, University of Zürich, Zürich, Switzerland., Rossing P; Steno Diabetes Center Copenhagen, Herlev, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Fenton RA; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Heerspink HJL; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, Groningen, the Netherlands., Hoorn EJ; Department of Internal Medicine, Division of Nephrology and Transplantation, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands. Electronic address: e.j.hoorn@erasmusmc.nl.
Source: Kidney international [Kidney Int] 2026 May 21. Date of Electronic Publication: 2026 May 21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0323470 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1755 (Electronic) Linking ISSN: 00852538 NLM ISO Abbreviation: Kidney Int Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1523-1755
DOI:10.1016/j.kint.2026.04.018