Twist1 overexpression models an aggressive subtype of pancreatic ductal adenocarcinoma in vivo.

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Title: Twist1 overexpression models an aggressive subtype of pancreatic ductal adenocarcinoma in vivo.
Authors: Khan MA; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA., Chang J; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA.; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.; Department of GU Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA., Song Y; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA., Shetty AC; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA., Nguyen T; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA.; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA., Waters DN; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA., Chowdhury DD; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA., Simms E; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA., Chan A; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA., Tseng HW; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA.; Department of GU Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA., Lam C; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA., Patel P; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA., Tran LT; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA., Chen J; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA., Wang JH; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA., Nugent K; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA., Ballew M; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA., Lemtiri-Chlieh G; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA., Carrieri FA; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA.; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA., Malek R; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA., Wang H; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.; GenoImmune Therapeutics, Wuhan, China., Thielman NRJ; Department of Immunology and Microbiology, Lake Erie College of Osteopathic Medicine, Erie, PA, USA., Li K; Department of Pancreatic Surgery West China Hospital, SCU, Chengdu, China., Park RJ; Department of GU Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA., Hwang WL; Center for Systems Biology, Center for Cancer Research, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Zheng L; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, MD, USA., Gabrielson K; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.; Department of Molecular and Comparative Pathobiology, Johns Hopkins University, School of Medicine, Baltimore, MD, USA., Tran PT; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA. pttran6@mdanderson.org.; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA. pttran6@mdanderson.org.; Department of GU Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA. pttran6@mdanderson.org.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, MD, USA. pttran6@mdanderson.org.; Department of Urology, James Buchanan Urological Institute, Johns Hopkins University, School of Medicine, Baltimore, MD, USA. pttran6@mdanderson.org., Lafargue A; Department of Radiation Oncology, Division of Translational Radiation Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD, USA. alafargue@mdanderson.org.; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA. alafargue@mdanderson.org.; Department of GU Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA. alafargue@mdanderson.org.
Source: Lab animal [Lab Anim (NY)] 2026 Aug; Vol. 55 (8), pp. 288-301. Date of Electronic Publication: 2026 May 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature America Country of Publication: United States NLM ID: 0417737 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-4475 (Electronic) Linking ISSN: 00937355 NLM ISO Abbreviation: Lab Anim (NY) Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1548-4475
DOI:10.1038/s41684-026-01729-2