Naringin and hesperidin protect ovarian granulosa cells from cisplatin-induced mitochondrial dysfunction by enhancing bioenergetics and mitophagy.

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Title: Naringin and hesperidin protect ovarian granulosa cells from cisplatin-induced mitochondrial dysfunction by enhancing bioenergetics and mitophagy.
Authors: Liu J; The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, 121000, China., Elmorsy EM; Center for Health Research, Northern Border University, Arar, 91431, Saudi Arabia. ekramy.elmorsy@nbu.edu.sa., Abdeen A; Department of Biochemistry, Faculty of Veterinary Medicine, Qena University, Qena, 83523, Egypt.; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Benha University, Toukh, 13736, Egypt., Anajirih N; Department of Emergency Medical Services, Faculty of Health Sciences, Al Qunfudhah, Umm Al-Qura University, Makkah, 21912, Saudi Arabia., Elgendy FS; Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Benha University, Benha, 13518, Egypt., Abdelkareem HM; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Benha University, Benha, 13518, Egypt.; Department of Medical Biochemistry, Molecular Biology and Physiology, Faculty of Medicine, Mutah University, Mutah, 61710, Jordan., Nasr HE; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Benha University, Benha, 13518, Egypt., Elwia SK; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Benha University, Benha, 13518, Egypt., Sherif MA; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., El-Shaer NO; Department of Physiology, Faculty of Medicine, Benha University, Benha, 13518, Egypt., El-Wakeel HS; Department of Physiology, Faculty of Medicine, Benha University, Benha, 13518, Egypt., Shukry M; Department of Biomedical Sciences, College of Veterinary Medicine, King Faisal University, Saudi Arabia, Al-Ahsa, 31982, Saudi Arabia. matta@kfu.edu.sa., Ibrahim SF; Department of Internal Medicine, College of Medicine, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia., Ali S; Department of Pharmacology, Faculty of Medicine, Benha University, Benha, 13518, Egypt., Gebba MA; Department of Oral Surgery and Diagnostic Sciences, Faculty of Dentistry Applied, Science Private University, Amman, Jordan., Abu-Almakarem AS; Department of Basic Medical Sciences, Faculty of Applied Medical Sciences, Al-Baha University, Al-Baha, 65525, Saudi Arabia., Ge Q; The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, 121000, China. gqd334880887@163.com.
Source: Biology direct [Biol Direct] 2026 May 22; Vol. 21 (1). Date of Electronic Publication: 2026 May 22.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101258412 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6150 (Electronic) Linking ISSN: 17456150 NLM ISO Abbreviation: Biol Direct Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1745-6150
DOI:10.1186/s13062-026-00830-3