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Naringin and hesperidin protect ovarian granulosa cells from cisplatin-induced mitochondrial dysfunction by enhancing bioenergetics and mitophagy.

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Title: Naringin and hesperidin protect ovarian granulosa cells from cisplatin-induced mitochondrial dysfunction by enhancing bioenergetics and mitophagy.
Authors: Liu J; The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, 121000, China., Elmorsy EM; Center for Health Research, Northern Border University, Arar, 91431, Saudi Arabia. ekramy.elmorsy@nbu.edu.sa., Abdeen A; Department of Biochemistry, Faculty of Veterinary Medicine, Qena University, Qena, 83523, Egypt.; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Benha University, Toukh, 13736, Egypt., Anajirih N; Department of Emergency Medical Services, Faculty of Health Sciences, Al Qunfudhah, Umm Al-Qura University, Makkah, 21912, Saudi Arabia., Elgendy FS; Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Benha University, Benha, 13518, Egypt., Abdelkareem HM; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Benha University, Benha, 13518, Egypt.; Department of Medical Biochemistry, Molecular Biology and Physiology, Faculty of Medicine, Mutah University, Mutah, 61710, Jordan., Nasr HE; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Benha University, Benha, 13518, Egypt., Elwia SK; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Benha University, Benha, 13518, Egypt., Sherif MA; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., El-Shaer NO; Department of Physiology, Faculty of Medicine, Benha University, Benha, 13518, Egypt., El-Wakeel HS; Department of Physiology, Faculty of Medicine, Benha University, Benha, 13518, Egypt., Shukry M; Department of Biomedical Sciences, College of Veterinary Medicine, King Faisal University, Saudi Arabia, Al-Ahsa, 31982, Saudi Arabia. matta@kfu.edu.sa., Ibrahim SF; Department of Internal Medicine, College of Medicine, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia., Ali S; Department of Pharmacology, Faculty of Medicine, Benha University, Benha, 13518, Egypt., Gebba MA; Department of Oral Surgery and Diagnostic Sciences, Faculty of Dentistry Applied, Science Private University, Amman, Jordan., Abu-Almakarem AS; Department of Basic Medical Sciences, Faculty of Applied Medical Sciences, Al-Baha University, Al-Baha, 65525, Saudi Arabia., Ge Q; The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, 121000, China. gqd334880887@163.com.
Source: Biology direct [Biol Direct] 2026 May 22; Vol. 21 (1). Date of Electronic Publication: 2026 May 22.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101258412 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6150 (Electronic) Linking ISSN: 17456150 NLM ISO Abbreviation: Biol Direct Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Naringin and hesperidin protect ovarian granulosa cells from cisplatin-induced mitochondrial dysfunction by enhancing bioenergetics and mitophagy.
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  Data: <searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, 121000, China.<br /><searchLink fieldCode="AU" term="%22Elmorsy+EM%22">Elmorsy EM</searchLink>; Center for Health Research, Northern Border University, Arar, 91431, Saudi Arabia. ekramy.elmorsy@nbu.edu.sa.<br /><searchLink fieldCode="AU" term="%22Abdeen+A%22">Abdeen A</searchLink>; Department of Biochemistry, Faculty of Veterinary Medicine, Qena University, Qena, 83523, Egypt.; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Benha University, Toukh, 13736, Egypt.<br /><searchLink fieldCode="AU" term="%22Anajirih+N%22">Anajirih N</searchLink>; Department of Emergency Medical Services, Faculty of Health Sciences, Al Qunfudhah, Umm Al-Qura University, Makkah, 21912, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Elgendy+FS%22">Elgendy FS</searchLink>; Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Benha University, Benha, 13518, Egypt.<br /><searchLink fieldCode="AU" term="%22Abdelkareem+HM%22">Abdelkareem HM</searchLink>; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Benha University, Benha, 13518, Egypt.; Department of Medical Biochemistry, Molecular Biology and Physiology, Faculty of Medicine, Mutah University, Mutah, 61710, Jordan.<br /><searchLink fieldCode="AU" term="%22Nasr+HE%22">Nasr HE</searchLink>; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Benha University, Benha, 13518, Egypt.<br /><searchLink fieldCode="AU" term="%22Elwia+SK%22">Elwia SK</searchLink>; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Benha University, Benha, 13518, Egypt.<br /><searchLink fieldCode="AU" term="%22Sherif+MA%22">Sherif MA</searchLink>; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Shaer+NO%22">El-Shaer NO</searchLink>; Department of Physiology, Faculty of Medicine, Benha University, Benha, 13518, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Wakeel+HS%22">El-Wakeel HS</searchLink>; Department of Physiology, Faculty of Medicine, Benha University, Benha, 13518, Egypt.<br /><searchLink fieldCode="AU" term="%22Shukry+M%22">Shukry M</searchLink>; Department of Biomedical Sciences, College of Veterinary Medicine, King Faisal University, Saudi Arabia, Al-Ahsa, 31982, Saudi Arabia. matta@kfu.edu.sa.<br /><searchLink fieldCode="AU" term="%22Ibrahim+SF%22">Ibrahim SF</searchLink>; Department of Internal Medicine, College of Medicine, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ali+S%22">Ali S</searchLink>; Department of Pharmacology, Faculty of Medicine, Benha University, Benha, 13518, Egypt.<br /><searchLink fieldCode="AU" term="%22Gebba+MA%22">Gebba MA</searchLink>; Department of Oral Surgery and Diagnostic Sciences, Faculty of Dentistry Applied, Science Private University, Amman, Jordan.<br /><searchLink fieldCode="AU" term="%22Abu-Almakarem+AS%22">Abu-Almakarem AS</searchLink>; Department of Basic Medical Sciences, Faculty of Applied Medical Sciences, Al-Baha University, Al-Baha, 65525, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ge+Q%22">Ge Q</searchLink>; The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, 121000, China. gqd334880887@163.com.
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  Data: <searchLink fieldCode="JN" term="%22101258412%22">Biology direct</searchLink> [Biol Direct] 2026 May 22; Vol. 21 (1). <i>Date of Electronic Publication: </i>2026 May 22.
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