Fragment-Based Design of Targeted Covalent Inhibitors: The Scope and Limitation of Linking Approaches.

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Bibliographic Details
Title: Fragment-Based Design of Targeted Covalent Inhibitors: The Scope and Limitation of Linking Approaches.
Authors: Kollár L; Medicinal Chemistry Research Group and Drug Innovation Centre, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.; Department of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Budapest, Hungary., Mihalovits LM; Medicinal Chemistry Research Group and Drug Innovation Centre, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary., Bajusz D; Medicinal Chemistry Research Group and Drug Innovation Centre, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary., Knez D; Department of Medicinal Chemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia., Simon J; Medicinal Chemistry Research Group and Drug Innovation Centre, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.; MS Metabolomics Research Group, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary., Balcomb BH; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK.; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, UK., Fearon D; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK., Gobec S; Department of Medicinal Chemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia., Keserű GM; Medicinal Chemistry Research Group and Drug Innovation Centre, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.; Department of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Budapest, Hungary.
Source: ChemMedChem [ChemMedChem] 2026 May 27; Vol. 21 (10), pp. e202501108.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1860-7187
DOI:10.1002/cmdc.202501108