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Multiparametric MRI biomarkers in pediatric osteosarcoma: associations of ADC, necrosis, and tumor volume with histologic and clinical outcomes in a retrospective cohort study.

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Title: Multiparametric MRI biomarkers in pediatric osteosarcoma: associations of ADC, necrosis, and tumor volume with histologic and clinical outcomes in a retrospective cohort study.
Authors: Cruz IAND; Department of Diagnostic Imaging, Federal University of São Paulo, 715 - Rua Napoleão de Barros, Hospital São Paulo, São Paulo, 04023-900, Brazil. isabela.cruz@grupofleury.com.br.; Department of Musculoskeletal Radiology, Fleury S.A. (Brazil), São Paulo, Brazil. isabela.cruz@grupofleury.com.br., Fayad LM; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medicine, Baltimore, USA., Macedo CRPD; Department of Oncology, Support group for adolescents and children with cancer, São Paulo, Brazil., Perez PTK; Department of Diagnostic Imaging, Federal University of São Paulo, 715 - Rua Napoleão de Barros, Hospital São Paulo, São Paulo, 04023-900, Brazil.; Department of Musculoskeletal Radiology, Fleury S.A. (Brazil), São Paulo, Brazil., Pinto MBR; Department of Diagnostic Imaging, Federal University of São Paulo, 715 - Rua Napoleão de Barros, Hospital São Paulo, São Paulo, 04023-900, Brazil.; Department of Musculoskeletal Radiology, Fleury S.A. (Brazil), São Paulo, Brazil., Azevedo BH; Department of Diagnostic Imaging, Federal University of São Paulo, 715 - Rua Napoleão de Barros, Hospital São Paulo, São Paulo, 04023-900, Brazil., Carvalho AG; Department of Oncology, Support group for adolescents and children with cancer, São Paulo, Brazil., Lederman HM; Department of Diagnostic Imaging, Federal University of São Paulo, 715 - Rua Napoleão de Barros, Hospital São Paulo, São Paulo, 04023-900, Brazil.; Department of Oncology, Support group for adolescents and children with cancer, São Paulo, Brazil., Fernandes ARC; Department of Diagnostic Imaging, Federal University of São Paulo, 715 - Rua Napoleão de Barros, Hospital São Paulo, São Paulo, 04023-900, Brazil., Guimarães JB; Department of Diagnostic Imaging, Federal University of São Paulo, 715 - Rua Napoleão de Barros, Hospital São Paulo, São Paulo, 04023-900, Brazil.; Department of Musculoskeletal Radiology, Fleury S.A. (Brazil), São Paulo, Brazil.; Department of Oncology, Support group for adolescents and children with cancer, São Paulo, Brazil.
Source: Pediatric radiology [Pediatr Radiol] 2026 Jun; Vol. 56 (7), pp. 1572-1587. Date of Electronic Publication: 2026 May 23.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0365332 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1998 (Electronic) Linking ISSN: 03010449 NLM ISO Abbreviation: Pediatr Radiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1432-1998
DOI:10.1007/s00247-026-06665-4