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Aberrant activation of renal functional reserve and reduced tubule flow, but not obstruction, is associated with cystogenesis in Pkd2 mutant kidneys.

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Title: Aberrant activation of renal functional reserve and reduced tubule flow, but not obstruction, is associated with cystogenesis in Pkd2 mutant kidneys.
Authors: Thomas IN; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States., Rajendran S; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States., Li Z; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States., Haycraft CJ; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States., Croyle MJ; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States., Yoder BK; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Source: Function (Oxford, England) [Function (Oxf)] 2026 Jun 01; Vol. 7 (3), pp. e1142025. Date of Electronic Publication: 2026 May 23.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 101770668 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2633-8823 (Electronic) Linking ISSN: 26338823 NLM ISO Abbreviation: Function (Oxf) Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Aberrant activation of renal functional reserve and reduced tubule flow, but not obstruction, is associated with cystogenesis in Pkd2 mutant kidneys.
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  Data: <searchLink fieldCode="AU" term="%22Thomas+IN%22">Thomas IN</searchLink>; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States.<br /><searchLink fieldCode="AU" term="%22Rajendran+S%22">Rajendran S</searchLink>; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States.<br /><searchLink fieldCode="AU" term="%22Haycraft+CJ%22">Haycraft CJ</searchLink>; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States.<br /><searchLink fieldCode="AU" term="%22Croyle+MJ%22">Croyle MJ</searchLink>; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States.<br /><searchLink fieldCode="AU" term="%22Yoder+BK%22">Yoder BK</searchLink>; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States.
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  Data: <searchLink fieldCode="JN" term="%22101770668%22">Function (Oxford, England)</searchLink> [Function (Oxf)] 2026 Jun 01; Vol. 7 (3), pp. e1142025. <i>Date of Electronic Publication: </i>2026 May 23.
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  Data: Journal Article; Research Support, N.I.H., Extramural
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101770668 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2633-8823 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226338823%22">26338823 </searchLink><i>NLM ISO Abbreviation: </i>Function (Oxf) <i>Subsets: </i>MEDLINE
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        Value: 10.1152/function.114.2025
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      – Code: eng
        Text: English
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        StartPage: e1142025
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      – TitleFull: Aberrant activation of renal functional reserve and reduced tubule flow, but not obstruction, is associated with cystogenesis in Pkd2 mutant kidneys.
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            NameFull: Rajendran S
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              Text: 2026 Jun 01
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