An improved analytic workflow for serum mtDNA DAMP abundance, fragmentation and heteroplasmic variants: a retrospective analysis of acute respiratory failure patients.

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Title: An improved analytic workflow for serum mtDNA DAMP abundance, fragmentation and heteroplasmic variants: a retrospective analysis of acute respiratory failure patients.
Authors: Daly GT; Department of Pharmacology, University of South Alabama Whiddon College of Medicine, Mobile, 36688, USA., Hartsell EM; Department of Pharmacology, University of South Alabama Whiddon College of Medicine, Mobile, 36688, USA., Pastukh VM; Department of Pharmacology, University of South Alabama Whiddon College of Medicine, Mobile, 36688, USA., Roberts JT; Department of Pharmacology, University of South Alabama Whiddon College of Medicine, Mobile, 36688, USA., Haastrup AI; Department of Pharmacology, University of South Alabama Whiddon College of Medicine, Mobile, 36688, USA., Purcell LD; Atrium Health Wake Forest Baptist, Winston-Salem, 27157, USA., Mulekar MS; University of South Alabama College of Arts and Sciences, Department of Mathematics and Statistics, Mobile, 36688, USA., Files DC; Atrium Health Wake Forest Baptist, Winston-Salem, 27157, USA., Morris PE; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, 35233, USA., Gillespie MN; Department of Pharmacology, University of South Alabama Whiddon College of Medicine, Mobile, 36688, USA. mgillesp@southalabama.edu., Langley RJ; Department of Pharmacology, University of South Alabama Whiddon College of Medicine, Mobile, 36688, USA. rlangley@southalabama.edu.
Source: Scientific reports [Sci Rep] 2026 May 23. Date of Electronic Publication: 2026 May 23.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-026-51417-x