Extracellular vesicles from SB431542-conditioned human adipose-derived stem cells enhance in vitro and in vivo osteogenesis via a miR-20a-5p-BAMBI-BMP/canonical Wnt signaling axis.

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Title: Extracellular vesicles from SB431542-conditioned human adipose-derived stem cells enhance in vitro and in vivo osteogenesis via a miR-20a-5p-BAMBI-BMP/canonical Wnt signaling axis.
Authors: Huber J; Hagey Laboratory for Pediatric Regenerative Medicine, Stanford University School of Medicine, 257 Campus Drive, Stanford, CA 94305, USA.; Department of Plastic Surgery, BG University Hospital Bergmannsheil, Ruhr University Bochum, Bürkle de la Camp-Platz 1, Bochum 44789, Germany.; Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, 770 Welch Road, Stanford, CA 94304, USA.; Department of Surgery, Stanford University School of Medicine, 780 Welch Road, Stanford, CA 94304, USA., Longaker MT; Hagey Laboratory for Pediatric Regenerative Medicine, Stanford University School of Medicine, 257 Campus Drive, Stanford, CA 94305, USA.; Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, 770 Welch Road, Stanford, CA 94304, USA.; Department of Surgery, Stanford University School of Medicine, 780 Welch Road, Stanford, CA 94304, USA.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA 94305, USA., Quarto N; Hagey Laboratory for Pediatric Regenerative Medicine, Stanford University School of Medicine, 257 Campus Drive, Stanford, CA 94305, USA.; Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, 770 Welch Road, Stanford, CA 94304, USA.; Department of Surgery, Stanford University School of Medicine, 780 Welch Road, Stanford, CA 94304, USA.; Dipartimento di Scienze Biomediche Avanzate, Università degli Studi di Napoli Federico II, Via Pansini 11, Naples 80131, Italy.
Source: Stem cells translational medicine [Stem Cells Transl Med] 2026 May 18; Vol. 15 (6).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101578022 Publication Model: Print Cited Medium: Internet ISSN: 2157-6580 (Electronic) Linking ISSN: 21576564 NLM ISO Abbreviation: Stem Cells Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2157-6580
DOI:10.1093/stcltm/szag026