Vagal activation inhibits insulin release through neuronal nitric oxide synthase in obese male mice.
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| Title: | Vagal activation inhibits insulin release through neuronal nitric oxide synthase in obese male mice. |
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| Authors: | Hashiuchi E; Metabolism and Nutrition Research Unit, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa 920-1192, Japan., Inaba Y; Metabolism and Nutrition Research Unit, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa 920-1192, Japan.; Department of Physiology and Metabolism, Graduate School of Medical Sciences, Kanazawa University, Kanazawa 920-8640, Japan., Sugimoto H; Department of Biochemistry and Molecular Biology, Graduate School of Medicine, University of Tokyo, Tokyo 113-0033, Japan., Kimura K; Metabolism and Nutrition Research Unit, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa 920-1192, Japan., Watanabe H; Metabolism and Nutrition Research Unit, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa 920-1192, Japan., Kajino M; Division of Integrative Pathophysiology, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan., Asahara SI; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan., Kobayashi M; Metabolic Signal Research Center, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi 371-8512, Japan., Kikuchi O; Metabolic Signal Research Center, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi 371-8512, Japan., Hayashi Y; Department of Endocrinology, Research Institute of Environmental Medicine, Nagoya University, Nagoya 464-8601, Japan.; Department of Endocrinology, Nagoya University Graduate School of Medicine, Nagoya University, Nagoya 466-8550, Japan., Horike SI; Division of Integrated Omics Research, Research Center for Experimental Modeling of Human Disease, Kanazawa University, Kanazawa 920-8640, Japan., Daikoku T; Division of Animal Disease Model, Research Center for Experimental Modeling of Human Disease, Kanazawa University, Kanazawa 920-8640, Japan., Mieda M; Department of Integrative Neurophysiology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa 920-8640, Japan., Sakurai T; Institute of Medicine/International Institute for Integrative Sleep Medicine (WPI-IIIS) and Tsu-kuba Institute for Advanced Research (TIAR), University of Tsukuba, Tsukuba 305-8575, Japan., Sakai M; Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo 113-8602, Japan., Matsumoto M; Department of Molecular Metabolic Regulation, Diabetes Research Center, National Institute of Global Health and Medicine (NIGHM), Japan Institute for Health Security (JIHS), Tokyo 162-8655, Japan., Kitamura T; Metabolic Signal Research Center, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi 371-8512, Japan., Sato M; Mathematical Neuroscience Unit, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa 920-8640, Japan.; Laboratory of Developmental Neurobiology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa 920-8640, Japan., Ravnskjaer K; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense 5230, Denmark.; Center for Functional Genomics and Tissue Plasticity, University of Southern Denmark, Odense 5230, Denmark., Kasuga M; Institute of Medical Science, Asahi Life Foundation, Tokyo 103-0002, Japan., Tanida M; Department of Physiology II, Kanazawa Medical University, Uchinada 920-0293, Japan., Kuroda S; Department of Biochemistry and Molecular Biology, Graduate School of Medicine, University of Tokyo, Tokyo 113-0033, Japan.; Department of Biological Sciences, Graduate School of Science, University of Tokyo, Tokyo 113-0033, Japan., Inoue H; Division of Integrative Pathophysiology, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan.; Department of Systems Pathophysiology, Diabetes Therapeutics and Research Center, Tokushima University, Tokushima 770-8503, Japan. |
| Source: | Science signaling [Sci Signal] 2026 May 26; Vol. 19 (939), pp. eadz8805. Date of Electronic Publication: 2026 May 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1937-9145 |
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| DOI: | 10.1126/scisignal.adz8805 |
