Tumor-draining lymph nodes in ovarian cancer lack germinal centers but harbor tumor-reactive memory B cells clonally linked to intra-tumoral B cells.

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Title: Tumor-draining lymph nodes in ovarian cancer lack germinal centers but harbor tumor-reactive memory B cells clonally linked to intra-tumoral B cells.
Authors: Nathan N; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Paparoditis P; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Sarusi-Portuguez A; Mantoux Bioinformatics Institute of the Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot, Israel., Stoler-Barak L; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Horn HM; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Milo I; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Mazor RD; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Levy-Barda A; Biobank, Department of Pathology, Rabin Medical Center, Petah Tikva, Israel; Department of Digital Medical Technologies, Holon Institute of Technology, Holon, Israel., Yanichkin N; Department of Pathology, Rabin Medical Center, Petah Tikva, Israel., Borcherding N; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA., Blecher-Gonen R; The Crown Genomics Institute of the Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot, Israel., Ronen R; The Crown Genomics Institute of the Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot, Israel., Nachman IB; The Crown Genomics Institute of the Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot, Israel., Goliand I; Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Fellus-Alyagor L; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel., Salame TM; Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Sagi I; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Siloni GH; Department of Pathology, Sheba Medical Center, Ramat Gan, Israel., Gross M; Department of Otolaryngology-Head and Neck Surgery, Hadassah Medical Center, Jerusalem 9112102, Israel., Tenenbaum A; Department of Pediatrics, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Kent I; Department of Surgery, Division of Colorectal Surgery, Sheba Medical Center, Tel HaShomer, Ramat Gan, Israel; Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel., Keren L; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Raban O; Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel; Gynecologic Oncology Division, Helen Schneider Hospital for Women, Rabin Medical Center, Petah Tikva, Israel., Eitan R; Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel; Gynecologic Oncology Division, Helen Schneider Hospital for Women, Rabin Medical Center, Petah Tikva, Israel., Shulman Z; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel. Electronic address: ziv.shulman@weizmann.ac.il.
Source: Immunity [Immunity] 2026 Jun 09; Vol. 59 (6), pp. 1743-1757.e10. Date of Electronic Publication: 2026 May 26.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-4180
DOI:10.1016/j.immuni.2026.04.017