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NOX4 signatures in human abdominal aortic aneurysm reveal links to vascular cell plasticity, extracellular matrix remodeling and inflammation.

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Title: NOX4 signatures in human abdominal aortic aneurysm reveal links to vascular cell plasticity, extracellular matrix remodeling and inflammation.
Authors: Sinha A; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Kapalla M; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Schürmann C; Institute of Cardiovascular Physiology, Medical Faculty, Goethe University, Frankfurt am Main, Germany., Busch A; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Tabac R; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Mittag J; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Hamann B; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Sabater-Lleal M; Unit of Genomics of Complex Diseases, Institut de Recerca Sant Pau (IR SANT PAU), Sant Quintí 77-79, Barcelona, 17 08041, Spain; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain., Müglich M; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Kopaliani I; Department of Physiology, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Poitz DM; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Jänichen C; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Bundschuh RA; Department of Nuclear Medicine, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany; Institute of Radiopharmaceutical Cancer Research, Helmholtz Zentrum Dresden-Rossendorf (HZDR), Rossendorf, Germany., Klimova A; Institute for Medical Informatics and Biometry, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; Core Unit for Data Management and Analytics (CDMA), National Center for Tumor Diseases (NCT), Dresden, 01307, Germany., Reeps C; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Schröder K; Institute of Cardiovascular Physiology, Medical Faculty, Goethe University, Frankfurt am Main, Germany; German Center of Cardiovascular Research (DZHK), Partner Site RheinMain, Frankfurt, Germany., Hofmann A; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. Electronic address: anja.hofmann2@uniklinikum-dresden.de.
Source: Free radical biology & medicine [Free Radic Biol Med] 2026 Sep; Vol. 253, pp. 320-333. Date of Electronic Publication: 2026 May 25.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE
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  Data: NOX4 signatures in human abdominal aortic aneurysm reveal links to vascular cell plasticity, extracellular matrix remodeling and inflammation.
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  Data: <searchLink fieldCode="AU" term="%22Sinha+A%22">Sinha A</searchLink>; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Kapalla+M%22">Kapalla M</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Schürmann+C%22">Schürmann C</searchLink>; Institute of Cardiovascular Physiology, Medical Faculty, Goethe University, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Busch+A%22">Busch A</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Tabac+R%22">Tabac R</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Mittag+J%22">Mittag J</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Hamann+B%22">Hamann B</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Sabater-Lleal+M%22">Sabater-Lleal M</searchLink>; Unit of Genomics of Complex Diseases, Institut de Recerca Sant Pau (IR SANT PAU), Sant Quintí 77-79, Barcelona, 17 08041, Spain; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Müglich+M%22">Müglich M</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Kopaliani+I%22">Kopaliani I</searchLink>; Department of Physiology, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Poitz+DM%22">Poitz DM</searchLink>; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Jänichen+C%22">Jänichen C</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Bundschuh+RA%22">Bundschuh RA</searchLink>; Department of Nuclear Medicine, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany; Institute of Radiopharmaceutical Cancer Research, Helmholtz Zentrum Dresden-Rossendorf (HZDR), Rossendorf, Germany.<br /><searchLink fieldCode="AU" term="%22Klimova+A%22">Klimova A</searchLink>; Institute for Medical Informatics and Biometry, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; Core Unit for Data Management and Analytics (CDMA), National Center for Tumor Diseases (NCT), Dresden, 01307, Germany.<br /><searchLink fieldCode="AU" term="%22Reeps+C%22">Reeps C</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Schröder+K%22">Schröder K</searchLink>; Institute of Cardiovascular Physiology, Medical Faculty, Goethe University, Frankfurt am Main, Germany; German Center of Cardiovascular Research (DZHK), Partner Site RheinMain, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Hofmann+A%22">Hofmann A</searchLink>; Division of Vascular and Endovascular Surgery, Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. Electronic address: anja.hofmann2@uniklinikum-dresden.de.
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  Data: <searchLink fieldCode="JN" term="%228709159%22">Free radical biology & medicine</searchLink> [Free Radic Biol Med] 2026 Sep; Vol. 253, pp. 320-333. <i>Date of Electronic Publication: </i>2026 May 25.
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