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Development and preliminary physicochemical characterization of a Ramucirumab biosimilar candidate in CHO cells using shake-flask fed-batch culture.

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Title: Development and preliminary physicochemical characterization of a Ramucirumab biosimilar candidate in CHO cells using shake-flask fed-batch culture.
Authors: Cagatay E; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Turkey.; Izmir Biomedicine and Genome Center, Izmir, Turkey., Gungor Y; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Turkey.; Izmir Biomedicine and Genome Center, Izmir, Turkey., Ozturk SS; OzBio LLC, Dedham, MA, USA., Kayali HA; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Turkey. hulya.kayali@deu.edu.tr.; Izmir Biomedicine and Genome Center, Izmir, Turkey. hulya.kayali@deu.edu.tr.; Department of Chemistry, Faculty of Science, Dokuz Eylul University, Izmir, Turkey. hulya.kayali@deu.edu.tr.
Source: Bioprocess and biosystems engineering [Bioprocess Biosyst Eng] 2026 May 27. Date of Electronic Publication: 2026 May 27.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 101088505 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1615-7605 (Electronic) Linking ISSN: 16157591 NLM ISO Abbreviation: Bioprocess Biosyst Eng Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Development and preliminary physicochemical characterization of a Ramucirumab biosimilar candidate in CHO cells using shake-flask fed-batch culture.
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  Data: <searchLink fieldCode="AU" term="%22Cagatay+E%22">Cagatay E</searchLink>; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Turkey.; Izmir Biomedicine and Genome Center, Izmir, Turkey.<br /><searchLink fieldCode="AU" term="%22Gungor+Y%22">Gungor Y</searchLink>; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Turkey.; Izmir Biomedicine and Genome Center, Izmir, Turkey.<br /><searchLink fieldCode="AU" term="%22Ozturk+SS%22">Ozturk SS</searchLink>; OzBio LLC, Dedham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kayali+HA%22">Kayali HA</searchLink>; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Turkey. hulya.kayali@deu.edu.tr.; Izmir Biomedicine and Genome Center, Izmir, Turkey. hulya.kayali@deu.edu.tr.; Department of Chemistry, Faculty of Science, Dokuz Eylul University, Izmir, Turkey. hulya.kayali@deu.edu.tr.
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  Data: <searchLink fieldCode="JN" term="%22101088505%22">Bioprocess and biosystems engineering</searchLink> [Bioprocess Biosyst Eng] 2026 May 27. <i>Date of Electronic Publication: </i>2026 May 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%22">Springer-Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101088505 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1615-7605 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216157591%22">16157591 </searchLink><i>NLM ISO Abbreviation: </i>Bioprocess Biosyst Eng <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00449-026-03358-y
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              Text: 2026 May 27
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