Epigenome-wide association study of psilocybin-induced methylome changes in alcohol use disorder.

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Title: Epigenome-wide association study of psilocybin-induced methylome changes in alcohol use disorder.
Authors: Urban MM; Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany. m.urban@stud.uni-heidelberg.de.; Interdisciplinary Center for Neurosciences, University of Heidelberg, Heidelberg, Germany. m.urban@stud.uni-heidelberg.de., Zillich L; Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Freiburg, Germany.; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Rieser NM; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland., Herdener M; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland., Spanagel R; Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Vollenweider FX; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland., Preller KH; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland., Meinhardt MW; Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany. marcus.meinhardt@zi-mannheim.de.; Department of Molecular Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany. marcus.meinhardt@zi-mannheim.de.
Source: Translational psychiatry [Transl Psychiatry] 2026 May 26; Vol. 16 (1). Date of Electronic Publication: 2026 May 26.
Publication Type: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2158-3188
DOI:10.1038/s41398-026-03961-3