Sonic hedgehog reduces alveolar bone resorption by triggering the coupling of type H vessel formation and osteogenesis in a periodontitis model.

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Title: Sonic hedgehog reduces alveolar bone resorption by triggering the coupling of type H vessel formation and osteogenesis in a periodontitis model.
Authors: Zhou H; Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, China.; Department of Periodontology, College of Stomatology, Xi'an Jiaotong University, Xi'an, China., Qi YX; Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, China.; Department of Digital Oral Implantology and Prothodontics, College of Stomatology, Xi'an Jiaotong University, Xi'an, China., Ma SY; Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, China., Liu J; Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, China.; Department of Periodontology, College of Stomatology, Xi'an Jiaotong University, Xi'an, China., Zhu CH; Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, China.; Department of Periodontology, College of Stomatology, Xi'an Jiaotong University, Xi'an, China., Yu SC; Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, China.; Department of Periodontology, College of Stomatology, Xi'an Jiaotong University, Xi'an, China., Li A; Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, China. drliang@mail.xjtu.edu.cn.; Department of Periodontology, College of Stomatology, Xi'an Jiaotong University, Xi'an, China. drliang@mail.xjtu.edu.cn., Pei DD; Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, China. peidandan@xjtu.edu.cn.; Department of Digital Oral Implantology and Prothodontics, College of Stomatology, Xi'an Jiaotong University, Xi'an, China. peidandan@xjtu.edu.cn.
Source: BMC oral health [BMC Oral Health] 2026 May 26. Date of Electronic Publication: 2026 May 26.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101088684 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1472-6831 (Electronic) Linking ISSN: 14726831 NLM ISO Abbreviation: BMC Oral Health Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1472-6831
DOI:10.1186/s12903-026-08637-4