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TM4SF1-Directed Antibody-Drug Conjugates Selectively Destroy Newly Formed Blood Vessels Induced by VEGF-A.

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Title: TM4SF1-Directed Antibody-Drug Conjugates Selectively Destroy Newly Formed Blood Vessels Induced by VEGF-A.
Authors: Lin CI; Center for Vascular Biology Research, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02130, USA.; Riverview Hospital, 395 Westfield Rd., Noblesville, IN 46060, USA., Liu Y; Center for Vascular Biology Research, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02130, USA.; Department of Pharmacology, Shanxi Medical University, Xinjiannanlu 56, Taiyuan 030001, China., Sciuto TE; Center for Vascular Biology Research, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02130, USA., Merley A; Center for Vascular Biology Research, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02130, USA.; Center for Animal Resources and Education, Brown University, Providence, RI 02912, USA., Dvorak HF; Center for Vascular Biology Research, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02130, USA.; Angiex Inc., Cambridge, MA 02140, USA., Jaminet SS; Center for Vascular Biology Research, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02130, USA.; Angiex Inc., Cambridge, MA 02140, USA.
Source: International journal of molecular sciences [Int J Mol Sci] 2026 May 15; Vol. 27 (10). Date of Electronic Publication: 2026 May 15.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1422-0067
DOI:10.3390/ijms27104437