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Integrated transcriptomic and proteomic profiling implicates prostaglandin-nitric oxide network dysregulation in uterine microcirculatory impairment in primary dysmenorrhea.

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Title: Integrated transcriptomic and proteomic profiling implicates prostaglandin-nitric oxide network dysregulation in uterine microcirculatory impairment in primary dysmenorrhea.
Authors: Li Y; School of Pharmacy, Shandong University of Traditional Chinese Medicine (TCM), Jinan, China.; Department of Anesthesiology, the First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital; Shandong Institute of Anesthesia and Respiratory Critical Medicine; Shandong Provincial Clinical Research Center for Anesthesiology, Jinan, China., Yang Z; Shandong Academy of Chinese Medicine, Jinan, China., Yu B; Shandong Academy of Chinese Medicine, Jinan, China., Zhang X; Shandong Academy of Chinese Medicine, Jinan, China., Li X; Shandong Academy of Chinese Medicine, Jinan, China., Chen W; Shandong Academy of Chinese Medicine, Jinan, China., Yuan M; Jining Medical University, Jining, China., Sui Z; Shandong Academy of Chinese Medicine, Jinan, China., Zhang Y; Qilu Institute of Technology, Jinan, China., Hou W; Shandong Academy of Chinese Medicine, Jinan, China., Gao D; School of Pharmacy, Shandong University of Traditional Chinese Medicine (TCM), Jinan, China.
Source: Frontiers in immunology [Front Immunol] 2026 May 11; Vol. 17, pp. 1833346. Date of Electronic Publication: 2026 May 11 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1833346