Assessing the trustworthiness of health guidelines recommendations: the transparent, rigorous, useable, standardized, and trustworthy guide (TRUSTGUIDES) tools development.

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Title: Assessing the trustworthiness of health guidelines recommendations: the transparent, rigorous, useable, standardized, and trustworthy guide (TRUSTGUIDES) tools development.
Authors: Arienti C; Department of Biomedical Sciences, Clinical Epidemiology Research Centre (CERC), Humanitas University, Pieve Emanuele, Milan, Italy; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Neumann I; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Internal Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Akl EA; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Internal Medicine, Faculty of Medicine, American University of Beirut, Beirut, Lebanon., Pinto BS; MEDCIDS - Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal., Cruz MM; MEDCIDS - Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal., Boutron I; Université Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAe, Centre for Research in Epidemiology and Statistics, Centre d'Épidémiologie Clinique, Hôpital Hôtel Dieu, AP-HP, Cochrane France, Paris, France., Devane D; Evidence Synthesis Ireland and Cochrane Ireland, University of Galway, Galway, Ireland., Whaley P; Lancaster Environment Centre, Lancaster University, Lancaster, UK; The Evidence-Based Toxicology Collaboration at Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Parmelli E; Department of Biomedical Sciences, Clinical Epidemiology Research Centre (CERC), Humanitas University, Pieve Emanuele, Milan, Italy; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Saulle R; Department of Epidemiology, Lazio Regional Health Service-ASL Roma1, Rome, Italy., Cinquini M; International GRADE Working Group, HEAD of Laboratory of Methodology of Systematic Reviews and Guidelines Production, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Lazzarini SG; Department of Statistics and Quantitative Methods, University of Milano-Bicocca, Milan, Italy; IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy., Wiercioch W; Department of Health Research Methods, Evidence, and Impact, McMaster GRADE and Cochrane Canada Centres, McMaster University, Hamilton, Ontario, Canada., Alonso-Coello P; Institut de Recerca Sant Pau (IR Sant Pau) and CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain., Alper BS; Computable Publishing LLC, Scientific Knowledge Accelerator Foundation, Franklin, NC, USA., Azzam M; Department of Internal Medicine, Evidence-Based Practice and Impact Center, University of Kansas Medical Center, Kansas City, KS, USA., Awah N; Effective Basic Services Africa, Bamenda, Cameroon, Africa., Bala MM; Department of Hygiene and Dietetics, Chair of Epidemiology and Preventive Medicine, Jagiellonian University Medical College, Krakow, Poland., Barker TH; Health Evidence Synthesis, Recommendations and Impact (HESRI), School of Public Health, Adelaide University, Adelaide, Australia., Bartolomeos KK; Science for Health Department, World Health Organisation, Geneva, Switzerland., Bognanni A; Department of Biomedical Sciences, Clinical Epidemiology Research Centre (CERC), Humanitas University, Pieve Emanuele, Milan, Italy; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Brennan SS; School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia., Bruno V; Istituto Superiore di Sanità, Rome, Italy., Bruschettini M; Paediatrics, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden; Department of Research, Development, Education and Innovation, Cochrane Sweden, Lund University, Skåne University Hospital, Lund, Sweden., Capobussi M; Department of Biomedical Sciences for Health, University of Milan, Milan, Italy., Carrasco-Labra A; Centre for Integrative Global Oral Health, University of Pennsylvania, School of Dental Medicine, Philadelphia, USA., Chang S; Annals of Internal Medicine, Philadelphia, PA, USA., Choi M; National Evidence-Based Healthcare Collaborating Agency, Seoul, Korea., Clyne B; Department of Public Health and Epidemiology, RCSI University of Medicine and Health Sciences, Dublin, Ireland., Coclite D; Istituto Superiore di Sanità, Rome, Italy., Cruciani F; Department of Epidemiology, Lazio Regional Health Service-ASL Roma1, Rome, Italy., Cuello C; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Dahm P; Department of Urology, University of Minnesota, Minneapolis, USA., Darzi AJ; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Anesthesia, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada., Dewidar O; Bruyère Health Research Institute, University of Ottawa, Ottawa, Canada; Temerty Faculty of Medicine, University of Toronto, Toronto, Canada., Fei Y; Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Feller D; Department of General Practice, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands; Provincial Agency for Health of the Autonomous Province of Trento, Trento, Italy., Gartlehner G; Cochrane Austria University for Continuing Education Krems Krems Austria; RTI International, Center for Health Economics, Methods & Evidence Synthesis, Research Triangle Park, USA., Germini F; Department of Biomedical Sciences, Clinical Epidemiology Research Centre (CERC), Humanitas University, Pieve Emanuele, Milan, Italy; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Glick M; Center for Ingrative Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA., Gonzalez-Lorenzo M; International GRADE Working Group, HEAD of Laboratory of Methodology of Systematic Reviews and Guidelines Production, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Hassan C; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Khan H; Department of Public Health and Epidemiology, RCSI University of Medicine and Health Sciences, Dublin, Ireland., Klugar M; Institute of Health Information and Statistics of the Czech Republic, Prague, Czechia., Kredo T; Health Systems Research Unit, South African Medical Research Council, Cape Town, South Africa., Langendam M; Department of Public and Occupational Health, Amsterdam University Medical Centre, Amsterdam, The Netherlands; Amsterdam Public Health Research Institute, Methodology Program, Amsterdam, The Netherlands., Liang C; Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Meerpohl J; Institute for Evidence in Medicine, Medical Center & Faculty of Medicine, University of Freiburg, Freiburg, Germany; Cochrane Germany, Cochrane Germany Foundation, Freiburg, Germany., Minozzi S; Cochrane Review Group on Drugs and Alcohol, International GRADE Working Group, Laboratory of Methodology of Systematic Reviews and Guidelines Production, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Mitrova Z; Department of Epidemiology, Lazio Regional Health Service-ASL Roma1, Rome, Italy., Moja L; Department of Medicines and Health Products Policy and Standards, World Health Organization, Geneva, Switzerland., Morgano GP; European Commission Joint Research Centre, Ispra, Italy., Munn Z; Health Evidence Synthesis, Recommendations and Impact (HESRI), School of Public Health, Adelaide University, Adelaide, Australia., Mustafa RA; Division of Nephrology and Hypertension, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Napoletano A; Istituto Superiore di Sanità, Rome, Italy., Ngeh E; Research Organisation for Health Education and Rehabilitation-Cameroon (ROHER-CAM), Bamenda, Cameroon; School of Health and Society, University of Salford, Salford, UK., Nieuwlaat R; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Nonino F; Cochrane Italy, Unit of Epidemiology and Statistics, Institute of Neurological Sciences of Bologna, Bologna, Italy., Yepes-Nuñez JJ; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Ocagli H; Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Italy., Okwen P; Effective Basic Services Africa, Bamenda, Cameroon, Africa., Okwen T; Effective Basic Services Africa, Bamenda, Cameroon, Africa., Petri D; Istituto Superiore di Sanità, Rome, Italy., Piggott T; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Piovani D; Department of Biomedical Sciences, Clinical Epidemiology Research Centre (CERC), Humanitas University, Pieve Emanuele, Milan, Italy; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Poklepovic T; Department of Research in Biomedicine and Health, University of Split School of Medicine, Split, Croatia., Pollock D; Health Evidence Synthesis, Recommendations and Impact (HESRI), School of Public Health, Adelaide University, Adelaide, Australia., Punzo O; Istituto Superiore di Sanità, Rome, Italy., Qaseem A; American College of Physicians, Philadelphia, USA., Rashidian A; Department of Health Systems and Life Course, WHO Regional Office for the Eastern Mediterranean, Cairo, Egypt., Reinap M; WHO Regional Office for Europe, Copenhagen, Denmark., Ringsten M; Department of Research, Development, Education and Innovation, Cochrane Sweden, Lund University, Skåne University Hospital, Lund, Sweden., Rodin R; Public Health Agency of Canada, Ottawa, Ontario, Canada., Ruspi A; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Saif-Ur-Rahman KM; Evidence Synthesis Ireland and Cochrane Ireland, University of Galway, Galway, Ireland; Centre for Health Research Methods, Ireland GRADE Network, College of Medicine Nursing and Health Sciences, University of Galway, Galway, Ireland., Song Y; Iberoamerican Cochrane Centre, Biomedical Research, Institute Sant Pau (IIB Sant Pau), Barcelona, Spain., Stern C; Health Evidence Synthesis, Recommendations and Impact (HESRI), School of Public Health, Adelaide University, Adelaide, Australia., Superchi C; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Thomas R; World Health Organization, Geneva, Switzerland., Van Wyk SS; Centre for Evidence-Based Health Care, Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Vieira RJ; MEDCIDS - Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal; CINTESIS@RISE-Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal., Wang R; Center for Clinical Practice Guideline Development and Evaluation, Children's Hospital of Fudan University, Shanghai, China., Xia J; Nottingham Ningbo GRADE Centre, University of Nottingham, Ningbo, China., Yao X; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Oncology, McMaster University, Hamilton, Canada., Xie Y; Center for Clinical Practice Guideline Development and Evaluation, Children's Hospital of Fudan University, Shanghai, China., Davoli M; Department of Statistics and Quantitative Methods, University of Milano-Bicocca, Milan, Italy., Schünemann HJ; Department of Biomedical Sciences, Clinical Epidemiology Research Centre (CERC), Humanitas University, Pieve Emanuele, Milan, Italy; Charité, Universitätsmedizin-Berlin, Allergology and Immunology, Berlin, Germany. Electronic address: schuneh@mcmaster.ca.
Corporate Authors: TRUSTGUIDES Collaborative
Source: Journal of clinical epidemiology [J Clin Epidemiol] 2026 May 26; Vol. 197, pp. 112348. Date of Electronic Publication: 2026 May 26.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 8801383 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5921 (Electronic) Linking ISSN: 08954356 NLM ISO Abbreviation: J Clin Epidemiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1878-5921
DOI:10.1016/j.jclinepi.2026.112348