Depth of response to primary POMB/ACE chemotherapy predicts survival in poor prognosis germ-cell tumours.

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Title: Depth of response to primary POMB/ACE chemotherapy predicts survival in poor prognosis germ-cell tumours.
Authors: Hobbs E; Department of Medical Oncology, Charing Cross Hospital Campus of Imperial College London, London, UK., Ulrich L; Department of Medical Oncology, Charing Cross Hospital Campus of Imperial College London, London, UK., Sharma A; Department of Medical Oncology, Mount Vernon Hospital, London, UK., Sherpa G; Department of Medical Oncology, Charing Cross Hospital Campus of Imperial College London, London, UK., Howlett S; Department of Medical Oncology, Mount Vernon Hospital, London, UK., Maxwell A; Department of Medical Oncology, Charing Cross Hospital Campus of Imperial College London, London, UK., Short D; Department of Medical Oncology, Charing Cross Hospital Campus of Imperial College London, London, UK., Vazquez I; Department of Medical Oncology, Mount Vernon Hospital, London, UK., Agarwal R; Medical Oncology, University Hospitals of Northamptonshire NHS Trust, London, UK., Hrouda D; Department of Urology, Charing Cross Hospital Campus of Imperial College London, London, UK., Mannion E; Department of Histopathology, Charing Cross Hospital Campus of Imperial College London, London, UK., Wilkes EH; Department of North West London Pathology, Charing Cross Hospital Campus of Imperial College London, London, UK., Lozano-Kuehne J; Biostatistics Research Group, Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK., Maher E; Department of Surgery and Cancer, Imperial College London, London, UK., Rustin G; Department of Medical Oncology, Mount Vernon Hospital, London, UK., Tin T; Department of Medical Oncology, Charing Cross Hospital Campus of Imperial College London, London, UK., Gonzalez M; Department of Medical Oncology, Charing Cross Hospital Campus of Imperial College London, London, UK., Sarwar N; Department of Medical Oncology, Charing Cross Hospital Campus of Imperial College London, London, UK., Seckl MJ; Department of Medical Oncology, Charing Cross Hospital Campus of Imperial College London, London, UK., Ghorani E; Department of Medical Oncology, Charing Cross Hospital Campus of Imperial College London, London, UK. e.ghorani@imperial.ac.uk.
Source: British journal of cancer [Br J Cancer] 2026 May 28. Date of Electronic Publication: 2026 May 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1532-1827
DOI:10.1038/s41416-026-03464-4