Mitochondrial activity promotes neutrophil degranulation and endothelial dysfunction in systemic infections.
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| Title: | Mitochondrial activity promotes neutrophil degranulation and endothelial dysfunction in systemic infections. |
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| Authors: | Zakrzewski P; School of Cellular and Molecular Medicine, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Rice CM; School of Cellular and Molecular Medicine, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Naveh C; School of Cellular and Molecular Medicine, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Dowell I; School of Cellular and Molecular Medicine, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Fleming K; School of Cellular and Molecular Medicine, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Ramesh AV; Bristol Veterinary School, University of Bristol, Bristol, UK., Jones R; School of Cellular and Molecular Medicine, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Moura PL; Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, Huddinge, Sweden., Cela D; School of Cellular and Molecular Medicine, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Groves S; School of Cellular and Molecular Medicine, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Fletcher-Jones S; School of Cellular and Molecular Medicine, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Victory Y; School of Cellular and Molecular Medicine, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Bhima M; School of Cellular and Molecular Medicine, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Ebmeier S; Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK., Carey L; Bristol Medical School, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Butler M; Bristol Medical School, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Satchell SC; Bristol Medical School, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Berg A; Department of Medicine, Stavanger University Hospital, Stavanger, Norway.; Department of Medicine, Central Hospital of Maputo, Maputo, Mozambique., Palolite N; Department of Medicine, Central Hospital of Maputo, Maputo, Mozambique., Nyirenda J; Malawi-Liverpool Wellcome Trust Clinical Research Programme, Kamuzu University of Health Sciences, Blantyre, Malawi., Nyasulu W; Malawi-Liverpool Wellcome Trust Clinical Research Programme, Kamuzu University of Health Sciences, Blantyre, Malawi., Zgambo I; Malawi-Liverpool Wellcome Trust Clinical Research Programme, Kamuzu University of Health Sciences, Blantyre, Malawi., Attipa C; School of Infection and Immunity, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.; Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, UK.; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, UK., Wooldridge L; Bristol Veterinary School, University of Bristol, Bristol, UK., Davidson AD; School of Cellular and Molecular Medicine, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK., Cunnington A; Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK., Moxon CA; Malawi-Liverpool Wellcome Trust Clinical Research Programme, Kamuzu University of Health Sciences, Blantyre, Malawi.; School of Infection and Immunity, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Amulic B; School of Cellular and Molecular Medicine, Faculty of Health and Life Sciences, University of Bristol, Bristol, UK. borko.amulic@bristol.ac.uk. |
| Source: | EMBO molecular medicine [EMBO Mol Med] 2026 Jul; Vol. 18 (7), pp. 2691-2722. Date of Electronic Publication: 2026 May 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1757-4684 |
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| DOI: | 10.1038/s44321-026-00453-1 |
