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Targeting a genomic RNA G-quadruplex of dengue virus with small molecules as an alternative to protein-targeted therapeutics.

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Title: Targeting a genomic RNA G-quadruplex of dengue virus with small molecules as an alternative to protein-targeted therapeutics.
Authors: Kim YJ; Department of Biotechnology and Bioinformatics, College of Science and Technology, Korea University, 2511 Sejong-Ro, Sejong, 30019, Republic of Korea., Das M; Department of Precision Medicine, Graduate School of Biomedical Science (GSBMS), Sungkyunkwan University School of Medicine, Suwon, 16419, Republic of Korea., Song J; Department of Biotechnology and Bioinformatics, College of Science and Technology, Korea University, 2511 Sejong-Ro, Sejong, 30019, Republic of Korea., Das S; Department of Precision Medicine, Graduate School of Biomedical Science (GSBMS), Sungkyunkwan University School of Medicine, Suwon, 16419, Republic of Korea., Kim HJ; College of Pharmacy, Korea University, Sejong, 30019, Republic of Korea., Kim JK; College of Pharmacy, Korea University, Sejong, 30019, Republic of Korea., Lee KY; Department of Pharmacy, Sungkyunkwan University School of Medicine, Suwon, 16419, Republic of Korea., Kim KK; Department of Precision Medicine, Graduate School of Biomedical Science (GSBMS), Sungkyunkwan University School of Medicine, Suwon, 16419, Republic of Korea. kyeongkyu@skku.edu.; Institute for Antimicrobial Resistance and Therapeutics, Sungkyunkwan University School of Medicine, Suwon, 16419, Republic of Korea. kyeongkyu@skku.edu., Lee HR; Department of Biotechnology and Bioinformatics, College of Science and Technology, Korea University, 2511 Sejong-Ro, Sejong, 30019, Republic of Korea. leehr@korea.ac.kr.; Department of Lab Medicine, College of Medicine, Korea University, Seoul, 136-701, Republic of Korea. leehr@korea.ac.kr.
Source: Journal of biomedical science [J Biomed Sci] 2026 May 27; Vol. 33 (1). Date of Electronic Publication: 2026 May 27.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9421567 Publication Model: Electronic Cited Medium: Internet ISSN: 1423-0127 (Electronic) Linking ISSN: 10217770 NLM ISO Abbreviation: J Biomed Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1423-0127
DOI:10.1186/s12929-026-01262-x