CircRNA based bi-antigen vaccines against mpox virus induce potent and durable cross-protection in mice.
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| Title: | CircRNA based bi-antigen vaccines against mpox virus induce potent and durable cross-protection in mice. |
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| Authors: | Zhou J; State Key Laboratory of Virology and Biosafety, Center for Biosafety Mega Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, 430207, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Wang C; State Key Laboratory of Virology and Biosafety, Center for Biosafety Mega Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, 430207, China., Wu Y; State Key Laboratory of Virology and Biosafety, Center for Biosafety Mega Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, 430207, China., Zhao B; State Key Laboratory of Virology and Biosafety, Center for Biosafety Mega Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, 430207, China., Yang Y; Research and Development Department, Shanghai CirCode Biomedicine Co.Ltd, Shanghai, 200131, China., Ye T; State Key Laboratory of Virology and Biosafety, Center for Biosafety Mega Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, 430207, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Zhang K; State Key Laboratory of Virology and Biosafety, Center for Biosafety Mega Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, 430207, China., Li F; State Key Laboratory of Virology and Biosafety, Center for Biosafety Mega Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, 430207, China., Hu J; Research and Development Department, Shanghai CirCode Biomedicine Co.Ltd, Shanghai, 200131, China., Zhang K; Research and Development Department, Shanghai CirCode Biomedicine Co.Ltd, Shanghai, 200131, China., Liu F; Research and Development Department, Shanghai CirCode Biomedicine Co.Ltd, Shanghai, 200131, China., Wang W; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230027, China.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230027, China., Wang C; Department of Clinical Laboratory, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei Province, 441021, China., Wang Z; Research and Development Department, Shanghai CirCode Biomedicine Co.Ltd, Shanghai, 200131, China. wangzf@sustech.edu.cn.; Department of System Biology, School of Life Science, Southern University of Science and Technology, Shenzhen, China. wangzf@sustech.edu.cn., Chuai X; State Key Laboratory of Virology and Biosafety, Center for Biosafety Mega Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, 430207, China. chuaixia@wh.iov.cn., Chiu S; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230027, China. qiux@ustc.edu.cn.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230027, China. qiux@ustc.edu.cn.; Department of Laboratory Medicine, Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, Anhui, 230031, China. qiux@ustc.edu.cn. |
| Source: | Molecular biomedicine [Mol Biomed] 2026 May 28; Vol. 7 (1). Date of Electronic Publication: 2026 May 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Singapore Country of Publication: Singapore NLM ID: 9918283581406676 Publication Model: Electronic Cited Medium: Internet ISSN: 2662-8651 (Electronic) Linking ISSN: 26628651 NLM ISO Abbreviation: Mol Biomed Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2662-8651 |
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| DOI: | 10.1186/s43556-026-00474-9 |
